Tripelennamine hydrochlorideProduct ingredient for Tripelennamine

Show full entry for Tripelennamine
Name
Tripelennamine hydrochloride
Drug Entry
Tripelennamine

A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat asthma; HAY fever; urticaria; and rhinitis; and also in veterinary applications. Tripelennamine is administered by various routes, including topically.

See full entry for Tripelennamine
Accession Number
DBSALT000689
Structure
Similar Structures
Synonyms
Tripelennamine HCl
UNII
FWV8GJ56ZN
CAS Number
154-69-8
Weight
Average: 291.819
Monoisotopic: 291.150225426
Chemical Formula
C16H22ClN3
InChI Key
FSSICIQKZGUEAE-UHFFFAOYSA-N
InChI
InChI=1S/C16H21N3.ClH/c1-18(2)12-13-19(16-10-6-7-11-17-16)14-15-8-4-3-5-9-15;/h3-11H,12-14H2,1-2H3;1H
IUPAC Name
N-benzyl-N-[2-(dimethylamino)ethyl]pyridin-2-amine hydrochloride
SMILES
Cl.CN(C)CCN(CC1=CC=CC=C1)C1=CC=CC=N1
PubChem Compound
9066
ChemSpider
8713
ChEBI
774397
ChEMBL
CHEMBL1200446
Wikipedia
Tripelennamine
Predicted Properties
PropertyValueSource
Water Solubility2.84 mg/mLALOGPS
logP3.05ALOGPS
logP3.2Chemaxon
logS-2ALOGPS
pKa (Strongest Basic)8.76Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area19.37 Å2Chemaxon
Rotatable Bond Count6Chemaxon
Refractivity81.27 m3·mol-1Chemaxon
Polarizability30.11 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon