Biperiden hydrochlorideProduct ingredient for Biperiden

Show full entry for Biperiden
Name
Biperiden hydrochloride
Drug Entry
Biperiden

A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.

See full entry for Biperiden
Accession Number
DBSALT000804
Structure
Similar Structures
Synonyms
Biperiden HCl
UNII
K35N76CUHF
CAS Number
1235-82-1
Weight
Average: 347.922
Monoisotopic: 347.201592294
Chemical Formula
C21H30ClNO
InChI Key
RDNLAULGBSQZMP-UHFFFAOYSA-N
InChI
InChI=1S/C21H29NO.ClH/c23-21(19-7-3-1-4-8-19,11-14-22-12-5-2-6-13-22)20-16-17-9-10-18(20)15-17;/h1,3-4,7-10,17-18,20,23H,2,5-6,11-16H2;1H
IUPAC Name
1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenyl-3-(piperidin-1-yl)propan-1-ol hydrochloride
SMILES
Cl.OC(CCN1CCCCC1)(C1CC2CC1C=C2)C1=CC=CC=C1
PubChem Compound
92151
ChemSpider
83196
ChEBI
59171
ChEMBL
CHEMBL1201035
Wikipedia
Biperiden
Predicted Properties
PropertyValueSource
Water Solubility0.00426 mg/mLALOGPS
logP4.28ALOGPS
logP3.54Chemaxon
logS-4.9ALOGPS
pKa (Strongest Acidic)13.82Chemaxon
pKa (Strongest Basic)9.3Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area23.47 Å2Chemaxon
Rotatable Bond Count5Chemaxon
Refractivity97.02 m3·mol-1Chemaxon
Polarizability36.84 Å3Chemaxon
Number of Rings4Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon