Ethopropazine hydrochlorideProduct ingredient for Profenamine

Name
Ethopropazine hydrochloride
Drug Entry
Profenamine

Profenamine is a medication derived from phenothiazine. It is primarily used as an antidyskinetic to treat parkinsonism. It is sold under the trade names Parsidol in the United States and Parsidan in Canada.

Accession Number
DBSALT000813
Structure
Thumb
Synonyms
10-(2-(diethylamino)propyl)phenothiazine monohydrochloride / Ethopropazine HCl / ethopropazine monohydrochloride / N,N-diethyl-α-methyl-10H-phenothiazine-10-ethylamine hydrochloride / N,N-diethyl-α-methyl-10H-phenothiazine-10-ethylamine monohydrochloride / profenamine HCl / Profenamine hydrochloride / profenamine monohydrochloride
UNII
O00T1I1VRN
CAS Number
1094-08-2
Weight
Average: 348.933
Monoisotopic: 348.142697207
Chemical Formula
C19H25ClN2S
InChI Key
VXPCQISYVPFYRK-UHFFFAOYSA-N
InChI
InChI=1S/C19H24N2S.ClH/c1-4-20(5-2)15(3)14-21-16-10-6-8-12-18(16)22-19-13-9-7-11-17(19)21;/h6-13,15H,4-5,14H2,1-3H3;1H
IUPAC Name
diethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine hydrochloride
SMILES
Cl.CCN(CC)C(C)CN1C2=CC=CC=C2SC2=CC=CC=C12
External Links
KEGG Drug
D01118
PubChem Compound
122824
ChemSpider
109488
ChEBI
31568
ChEMBL
CHEMBL1200970
Wikipedia
Profenamine
Predicted Properties
PropertyValueSource
Water Solubility0.00524 mg/mLALOGPS
logP5.75ALOGPS
logP5ChemAxon
logS-4.8ALOGPS
pKa (Strongest Basic)9.6ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area6.48 Å2ChemAxon
Rotatable Bond Count5ChemAxon
Refractivity98 m3·mol-1ChemAxon
Polarizability36.24 Å3ChemAxon
Number of Rings3ChemAxon
Bioavailability1ChemAxon
Rule of FiveNoChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon