Sulfathiazole sodiumProduct ingredient for Sulfathiazole

Name
Sulfathiazole sodium
Drug Entry
Sulfathiazole

Sulfathiazole is a short-acting sulfa drug. It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide.

Except for those formulated for vaginal use, the FDA withdrew its approval for the use of all drug products containing sulfathiazole.1

Accession Number
DBSALT000848
Structure
Synonyms
Not Available
UNII
PV16N742VM
CAS Number
144-74-1
Weight
Average: 279.314
Monoisotopic: 279.011212634
Chemical Formula
C9H10N3NaO2S2
InChI Key
IMPWUOJNMQNKON-UHFFFAOYSA-N
InChI
InChI=1S/C9H10N3O2S2.Na/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9;/h1-4H,5-6,10H2;/q-1;+1
IUPAC Name
sodium 4-{[(4,5-dihydro-1,3-thiazol-2-yl)azanidyl]sulfonyl}aniline
SMILES
[Na+].NC1=CC=C(C=C1)S(=O)(=O)[N-]C1=NCCS1
PubChem Compound
45357965
ChemSpider
21513935
Predicted Properties
PropertyValueSource
Water Solubility2.37 mg/mLALOGPS
logP0.53ALOGPS
logP0.92Chemaxon
logS-2.1ALOGPS
pKa (Strongest Acidic)10.53Chemaxon
pKa (Strongest Basic)4.05Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count5Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area81.75 Å2Chemaxon
Rotatable Bond Count1Chemaxon
Refractivity64.79 m3·mol-1Chemaxon
Polarizability24.06 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon