Sulfathiazole sodiumProduct ingredient for Sulfathiazole
- Name
- Sulfathiazole sodium
- Drug Entry
- Sulfathiazole
Sulfathiazole is a short-acting sulfa drug. It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide.
Except for those formulated for vaginal use, the FDA withdrew its approval for the use of all drug products containing sulfathiazole.1
- Accession Number
- DBSALT000848
- Structure
- Synonyms
- Not Available
- UNII
- PV16N742VM
- CAS Number
- 144-74-1
- Weight
- Average: 279.314
Monoisotopic: 279.011212634 - Chemical Formula
- C9H10N3NaO2S2
- InChI Key
- IMPWUOJNMQNKON-UHFFFAOYSA-N
- InChI
- InChI=1S/C9H10N3O2S2.Na/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9;/h1-4H,5-6,10H2;/q-1;+1
- IUPAC Name
- sodium 4-{[(4,5-dihydro-1,3-thiazol-2-yl)azanidyl]sulfonyl}aniline
- SMILES
- [Na+].NC1=CC=C(C=C1)S(=O)(=O)[N-]C1=NCCS1
- External Links
- Predicted Properties
Property Value Source Water Solubility 2.37 mg/mL ALOGPS logP 0.53 ALOGPS logP 0.92 Chemaxon logS -2.1 ALOGPS pKa (Strongest Acidic) 10.53 Chemaxon pKa (Strongest Basic) 4.05 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 81.75 Å2 Chemaxon Rotatable Bond Count 1 Chemaxon Refractivity 64.79 m3·mol-1 Chemaxon Polarizability 24.06 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon