Guanadrel sulfateProduct ingredient for Guanadrel
- Name
- Guanadrel sulfate
- Drug Entry
- Guanadrel
Guanadrel is an antihypertensive agent and postganglionic adrenergic blocking agent.
- Accession Number
- DBSALT000889
- Structure
Structure for Guanadrel sulfate (DBSALT000889)
- Synonyms
- 1,4-dioxaspiro(4.5)dec-2-ylmethyl)guanidine sulfate (2:1) / 1,4-dioxaspiro(4.5)dec-2-ylmethyl)guanidine sulphate (2:1) / Guanadrel sulphate
- UNII
- MT147RMO91
- CAS Number
- 22195-34-2
- Weight
- Average: 524.63
Monoisotopic: 524.262833446 - Chemical Formula
- C20H40N6O8S
- InChI Key
- RTEVGQJRTFFMLL-UHFFFAOYSA-N
- InChI
- InChI=1S/2C10H19N3O2.H2O4S/c2*11-9(12)13-6-8-7-14-10(15-8)4-2-1-3-5-10;1-5(2,3)4/h2*8H,1-7H2,(H4,11,12,13);(H2,1,2,3,4)
- IUPAC Name
- bis(N-({1,4-dioxaspiro[4.5]decan-2-yl}methyl)guanidine); sulfuric acid
- SMILES
- OS(O)(=O)=O.NC(=N)NCC1COC2(CCCCC2)O1.NC(=N)NCC1COC2(CCCCC2)O1
- External Links
- PubChem Compound
- 16052006
- ChemSpider
- 61826
- ChEBI
- 5556
- ChEMBL
- CHEMBL3184143
- Wikipedia
- Guanadrel
- Predicted Properties
Property Value Source Water Solubility 1.73 mg/mL ALOGPS logP -0.18 ALOGPS logP 0.68 Chemaxon logS -2.1 ALOGPS pKa (Strongest Basic) 12.02 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 80.36 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 66.83 m3·mol-1 Chemaxon Polarizability 23.47 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon