Alprenolol hydrochlorideProduct ingredient for Alprenolol

Show full entry for Alprenolol
Name
Alprenolol hydrochloride
Drug Entry
Alprenolol

One of the adrenergic beta-antagonists used as an antihypertensive, anti-anginal, and anti-arrhythmic agent. Alprenolol is no longer marketed by AstraZeneca, but may still be available in generic varieties.

See full entry for Alprenolol
Accession Number
DBSALT000932
Structure
Similar Structures
Synonyms
Alprenolol HCl
UNII
2502C2OIRK
CAS Number
13707-88-5
Weight
Average: 285.81
Monoisotopic: 285.1495567
Chemical Formula
C15H24ClNO2
InChI Key
RRCPAXJDDNWJBI-UHFFFAOYSA-N
InChI
InChI=1S/C15H23NO2.ClH/c1-4-7-13-8-5-6-9-15(13)18-11-14(17)10-16-12(2)3;/h4-6,8-9,12,14,16-17H,1,7,10-11H2,2-3H3;1H
IUPAC Name
1-[2-(prop-2-en-1-yl)phenoxy]-3-[(propan-2-yl)amino]propan-2-ol hydrochloride
SMILES
Cl.CC(C)NCC(O)COC1=CC=CC=C1CC=C
PubChem Compound
66368
ChemSpider
59744
ChEBI
31191
ChEMBL
CHEMBL1256179
Predicted Properties
PropertyValueSource
Water Solubility0.188 mg/mLALOGPS
logP2.59ALOGPS
logP2.69Chemaxon
logS-3.1ALOGPS
pKa (Strongest Acidic)14.09Chemaxon
pKa (Strongest Basic)9.67Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area41.49 Å2Chemaxon
Rotatable Bond Count8Chemaxon
Refractivity74.66 m3·mol-1Chemaxon
Polarizability29.34 Å3Chemaxon
Number of Rings1Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon