Sevelamer carbonateProduct ingredient for Sevelamer

Show full entry for Sevelamer
Name
Sevelamer carbonate
Drug Entry
Sevelamer

Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.

See full entry for Sevelamer
Accession Number
DBSALT001006
Structure
Similar Structures
Synonyms
Sevelamer carbonate
UNII
9YCX42I8IU
CAS Number
845273-93-0
Weight
Average: 211.64
Monoisotopic: 211.0611356
Chemical Formula
C7H14ClNO4
InChI Key
PADGNZFOVSZIKZ-UHFFFAOYSA-N
InChI
InChI=1S/C3H5ClO.C3H7N.CH2O3/c4-1-3-2-5-3;1-2-3-4;2-1(3)4/h3H,1-2H2;2H,1,3-4H2;(H2,2,3,4)
IUPAC Name
2-(chloromethyl)oxirane prop-2-en-1-aminium hydrogen carbonate
SMILES
[NH3+]CC=C.OC([O-])=O.ClCC1CO1
ChemSpider
9768466
ChEMBL
CHEMBL1201799
Wikipedia
Sevelamer
Predicted Properties
PropertyValueSource
Water Solubility60.7 mg/mLALOGPS
logP0.52ALOGPS
logP0.68Chemaxon
logS-0.29ALOGPS
pKa (Strongest Basic)-4.2Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count1Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area12.53 Å2Chemaxon
Rotatable Bond Count2Chemaxon
Refractivity20.06 m3·mol-1Chemaxon
Polarizability8.33 Å3Chemaxon
Number of Rings1Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon