Indoramin hydrochlorideProduct ingredient for Indoramin

Name
Indoramin hydrochloride
Drug Entry
Indoramin

Indoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese. It is a selective alpha-1 adrenergic antagonist with no reflex tachycardia and direct myocardial depression action.

Accession Number
DBSALT001077
Structure
Synonyms
Indoramin HCl
UNII
DQ0Z3K8W92
CAS Number
38821-52-2
Weight
Average: 383.92
Monoisotopic: 383.1764402
Chemical Formula
C22H26ClN3O
InChI Key
AFJSFHAKSSWOKG-UHFFFAOYSA-N
InChI
InChI=1S/C22H25N3O.ClH/c26-22(17-6-2-1-3-7-17)24-19-11-14-25(15-12-19)13-10-18-16-23-21-9-5-4-8-20(18)21;/h1-9,16,19,23H,10-15H2,(H,24,26);1H
IUPAC Name
N-{1-[2-(1H-indol-3-yl)ethyl]piperidin-4-yl}benzamide hydrochloride
SMILES
Cl.O=C(NC1CCN(CCC2=CNC3=C2C=CC=C3)CC1)C1=CC=CC=C1
ChemSpider
34932
ChEMBL
CHEMBL2104941
Predicted Properties
PropertyValueSource
Water Solubility0.00863 mg/mLALOGPS
logP3.4ALOGPS
logP3.19Chemaxon
logS-4.6ALOGPS
pKa (Strongest Acidic)15.09Chemaxon
pKa (Strongest Basic)9Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area48.13 Å2Chemaxon
Rotatable Bond Count5Chemaxon
Refractivity105.94 m3·mol-1Chemaxon
Polarizability40.68 Å3Chemaxon
Number of Rings4Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon