Enviomycin sulfateProduct ingredient for Enviomycin
- Name
- Enviomycin sulfate
- Drug Entry
- Enviomycin
Cyclic basic peptide related to viomycin. It is isolated from an induced mutant of Streptomyces griseoverticillatus var. tuberacticus and acts as an antitubercular agent with less ototoxicity than tuberactinomycin.
- Accession Number
- DBSALT001086
- Structure
Structure for Enviomycin sulfate (DBSALT001086)
- Synonyms
- Not Available
- UNII
- 67846BXW65
- CAS Number
- 53760-33-1
- Weight
- Average: 1665.62
Monoisotopic: 1664.553308428 - Chemical Formula
- C50H92N26O32S3
- InChI Key
- DZKQVWCTFCSEKF-QOEBQMAPSA-N
- InChI
- InChI=1S/2C25H43N13O10.3H2O4S/c2*26-3-1-16(41)10(27)5-17(42)33-12-6-31-23(47)18(11-2-4-30-24(28)37-11)38-20(44)13(7-32-25(29)48)34-21(45)14(8-39)36-22(46)15(9-40)35-19(12)43;3*1-5(2,3)4/h2*7,10-12,14-16,18,39-41H,1-6,8-9,26-27H2,(H,31,47)(H,33,42)(H,34,45)(H,35,43)(H,36,46)(H,38,44)(H3,28,30,37)(H3,29,32,48);3*(H2,1,2,3,4)/b2*13-7-;;;/t2*10-,11-,12+,14+,15+,16-,18+;;;/m11.../s1
- IUPAC Name
- bis((3R,4R)-3,6-diamino-N-[(3S,6Z,9S,12S,15S)-3-[(4R)-2-amino-3,4,5,6-tetrahydropyrimidin-4-yl]-6-[(carbamoylamino)methylidene]-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-1,4,7,10,13-pentaazacyclohexadecan-15-yl]-4-hydroxyhexanamide); tris(sulfuric acid)
- SMILES
- OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.[H][C@@]1(CCN=C(N)N1)[C@]1([H])NC(=O)\C(NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CNC1=O)NC(=O)C[C@@H](N)[C@H](O)CCN)=C\NC(N)=O.[H][C@@]1(CCN=C(N)N1)[C@]1([H])NC(=O)\C(NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CNC1=O)NC(=O)C[C@@H](N)[C@H](O)CCN)=C\NC(N)=O
- External Links
- ChemSpider
- 34985959
- Predicted Properties
Property Value Source Water Solubility 2.56 mg/mL ALOGPS logP -3.5 ALOGPS logP -12 Chemaxon logS -2.4 ALOGPS pKa (Strongest Acidic) 8.71 Chemaxon pKa (Strongest Basic) 10.52 Chemaxon Physiological Charge 3 Chemaxon Hydrogen Acceptor Count 15 Chemaxon Hydrogen Donor Count 15 Chemaxon Polar Surface Area 392.86 Å2 Chemaxon Rotatable Bond Count 20 Chemaxon Refractivity 161.87 m3·mol-1 Chemaxon Polarizability 65.92 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon