Ciclopirox olamineProduct ingredient for Ciclopirox
- Name
- Ciclopirox olamine
- Drug Entry
- Ciclopirox
Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. In particular, the agent is especially effective in treating Tinea versicolor.
- Accession Number
- DBSALT001147
- Structure
- Synonyms
- Not Available
- External IDs
- HOE 296 / HOE-296
- UNII
- 50MD4SB4AP
- CAS Number
- 41621-49-2
- Weight
- Average: 268.357
Monoisotopic: 268.178692641 - Chemical Formula
- C14H24N2O3
- InChI Key
- MBRHNTMUYWQHMR-UHFFFAOYSA-N
- InChI
- InChI=1S/C12H17NO2.C2H7NO/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10;3-1-2-4/h7-8,10,15H,2-6H2,1H3;4H,1-3H2
- IUPAC Name
- 2-aminoethan-1-ol; 6-cyclohexyl-1-hydroxy-4-methyl-1,2-dihydropyridin-2-one
- SMILES
- NCCO.CC1=CC(=O)N(O)C(=C1)C1CCCCC1
- External Links
- ChemSpider
- 35605
- ChEMBL
- CHEMBL242580
- Wikipedia
- Ciclopirox
- Predicted Properties
Property Value Source Water Solubility 1.41 mg/mL ALOGPS logP 2.15 ALOGPS logP 2.22 Chemaxon logS -2.2 ALOGPS pKa (Strongest Acidic) 6.84 Chemaxon pKa (Strongest Basic) -6.2 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 40.54 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 60.91 m3·mol-1 Chemaxon Polarizability 23.13 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon