Lanthanum carbonate hydrateProduct ingredient for Lanthanum carbonate
- Name
- Lanthanum carbonate hydrate
- Drug Entry
- Lanthanum carbonate
Lanthanum carbonate is a phosphate binder commonly used in clinical practice. It is marketed under the trade name Fosrenol by Shire Pharmaceuticals. It is the largest of all pills filled in community pharmacies. Sometimes patients forget that Fosrenol is not swallowed whole, but instead should be chewed. This has led to severe choking. It is prescribed for treating high phosphate levels, mainly found in patients with chronic kidney disease. Lanthanum should be taken with meals and binds to phosphate in the diet, preventing phosphate absorption in the intestine.
- Accession Number
- DBSALT001176
- Structure
Structure for Lanthanum carbonate hydrate (DBSALT001176)
- Synonyms
- Dilanthanum tricarbonate hydrate / Lanthanum (III) carbonate hydrate / Lanthanum carbonate pentahydrate / Lanthanum carbonate tetrahydrate
- UNII
- 490D9F069T
- CAS Number
- 54451-24-0
- Weight
- Average: 529.895
Monoisotopic: 529.80921 - Chemical Formula
- C3H8La2O13
- InChI Key
- PKOQIYFBOVTYOH-UHFFFAOYSA-H
- InChI
- InChI=1S/3CH2O3.2La.4H2O/c3*2-1(3)4;;;;;;/h3*(H2,2,3,4);;;4*1H2/q;;;2*+3;;;;/p-6
- IUPAC Name
- dilanthanum(3+) tetrahydrate tricarbonate
- SMILES
- O.O.O.O.[La+3].[La+3].[O-]C([O-])=O.[O-]C([O-])=O.[O-]C([O-])=O
- External Links
- Human Metabolome Database
- HMDB0013711
- Predicted Properties
Property Value Source Water Solubility 31.0 mg/mL ALOGPS logP 0.65 ALOGPS logP 0.25 Chemaxon logS -1.2 ALOGPS pKa (Strongest Acidic) 3.5 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 63.19 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 31.17 m3·mol-1 Chemaxon Polarizability 3.52 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon