Fluphenazine hydrochlorideProduct ingredient for Fluphenazine
- Name
- Fluphenazine hydrochloride
- Drug Entry
- Fluphenazine
A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.
- Accession Number
- DBSALT000288 (DBSALT001197)
- Structure
- Synonyms
- Fluphenazine diHCl / Fluphenazine dihydrochloride / Fluphenazine HCl
- External IDs
- SQUIBB 4918
- UNII
- ZOU145W1XL
- CAS Number
- 146-56-5
- Weight
- Average: 510.443
Monoisotopic: 509.128223252 - Chemical Formula
- C22H28Cl2F3N3OS
- InChI Key
- MBHNWCYEGXQEIT-UHFFFAOYSA-N
- InChI
- InChI=1S/C22H26F3N3OS.2ClH/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29;;/h1-2,4-7,16,29H,3,8-15H2;2*1H
- IUPAC Name
- 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol dihydrochloride
- SMILES
- Cl.Cl.OCCN1CCN(CCCN2C3=CC=CC=C3SC3=C2C=C(C=C3)C(F)(F)F)CC1
- External Links
- PubChem Compound
- 67356
- ChemSpider
- 60687
- ChEBI
- 5126
- ChEMBL
- CHEMBL1448187
- Wikipedia
- Fluphenazine
- Predicted Properties
Property Value Source Water Solubility 0.019 mg/mL ALOGPS logP 4.4 ALOGPS logP 3.97 Chemaxon logS -4.4 ALOGPS pKa (Strongest Acidic) 15.59 Chemaxon pKa (Strongest Basic) 7.81 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 29.95 Å2 Chemaxon Rotatable Bond Count 7 Chemaxon Refractivity 117.27 m3·mol-1 Chemaxon Polarizability 45.07 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule Yes Chemaxon