Mometasone furoate monohydrateProduct ingredient for Mometasone furoate
- Name
- Mometasone furoate monohydrate
- Drug Entry
- Mometasone furoate
Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditionsLabel14,15. It has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone and higher than many other corticosteroids as well2. Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different indicationsLabel14,15.
- Accession Number
- DBSALT001244
- Structure
- Synonyms
- Not Available
- UNII
- MTW0WEG809
- CAS Number
- 141646-00-6
- Weight
- Average: 539.45
Monoisotopic: 538.1525088 - Chemical Formula
- C27H32Cl2O7
- InChI Key
- AQCCVUHZMIMSIB-HRVPQZBTSA-N
- InChI
- InChI=1S/C27H30Cl2O6.H2O/c1-15-11-19-18-7-6-16-12-17(30)8-9-24(16,2)26(18,29)21(31)13-25(19,3)27(15,22(32)14-28)35-23(33)20-5-4-10-34-20;/h4-5,8-10,12,15,18-19,21,31H,6-7,11,13-14H2,1-3H3;1H2/t15-,18+,19+,21+,24+,25+,26+,27+;/m1./s1
- IUPAC Name
- (1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-chloro-1-(2-chloroacetyl)-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl furan-2-carboxylate hydrate
- SMILES
- O.[H][C@@]12C[C@@H](C)[C@](OC(=O)C3=CC=CO3)(C(=O)CCl)[C@@]1(C)C[C@H](O)[C@@]1(Cl)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
- External Links
- ChemSpider
- 8069123
- Wikipedia
- Mometasone
- Predicted Properties
Property Value Source Water Solubility 0.0108 mg/mL ALOGPS logP 4.27 ALOGPS logP 5.06 Chemaxon logS -4.7 ALOGPS pKa (Strongest Acidic) 13.84 Chemaxon pKa (Strongest Basic) -3.1 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 93.81 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 132.5 m3·mol-1 Chemaxon Polarizability 52.2 Å3 Chemaxon Number of Rings 5 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon