Tetrahydrozoline hydrochlorideProduct ingredient for Tetryzoline

Name
Tetrahydrozoline hydrochloride
Drug Entry
Tetryzoline

Tetryzoline (also known as Tetrahydrozoline), a derivative of imidazoline, is found in over-the-counter eye drops and nasal sprays. Other derivatives include naphazoline, oxymetazoline, and xylometazoline. Johnson and Johnson manufactures tetryzoline eye drops under the brand Visine ®.

Accession Number
DBSALT001254
Structure
Thumb
Synonyms
Tetrahydrozoline HCl
UNII
0YZT43HS7D
CAS Number
522-48-5
Weight
Average: 236.74
Monoisotopic: 236.1080263
Chemical Formula
C13H17ClN2
InChI Key
BJORNXNYWNIWEY-UHFFFAOYSA-N
InChI
InChI=1S/C13H16N2.ClH/c1-2-6-11-10(4-1)5-3-7-12(11)13-14-8-9-15-13;/h1-2,4,6,12H,3,5,7-9H2,(H,14,15);1H
IUPAC Name
2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole hydrochloride
SMILES
Cl.C1CN=C(N1)C1CCCC2=CC=CC=C12
External Links
ChemSpider
10200
ChEMBL
CHEMBL1200413
Wikipedia
Tetryzoline
Predicted Properties
PropertyValueSource
Water Solubility0.239 mg/mLALOGPS
logP3.11ALOGPS
logP2.24ChemAxon
logS-2.9ALOGPS
pKa (Strongest Basic)10.17ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area24.39 Å2ChemAxon
Rotatable Bond Count1ChemAxon
Refractivity61.48 m3·mol-1ChemAxon
Polarizability23.01 Å3ChemAxon
Number of Rings3ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon