Silibinin dihemisuccinate disodiumProduct ingredient for Silibinin

Name
Silibinin dihemisuccinate disodium
Drug Entry
Silibinin

Silibinin is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin and others. Silibinin is presented as a mixture of two diastereomers, silybin A and silybin B, which are found in an approximately equimolar ratio. Both in vitro and animal research suggest that silibinin has hepatoprotective (antihepatotoxic) properties that protect liver cells against toxins. Silibinin has also demonstrated in vitro anti-cancer effects against human prostate adenocarcinoma cells, estrogen-dependent and -independent human breast carcinoma cells, human ectocervical carcinoma cells, human colon cancer cells, and both small and nonsmall human lung carcinoma cells.

Accession Number
DBSALT001287
Structure
Synonyms
DISODIUM SILIBININ DIHEMISUCCINATE / SILIBININ-C-2',3-DIHYDROGENSUCCINATE, DISODIUM SALT / SILYBIN SODIUM HEMISUCCINATE
UNII
57LSQ377IE
CAS Number
1265089-66-4
Not Available
Predicted Properties
Not Available