Dapiprazole hydrochlorideProduct ingredient for Dapiprazole

Name
Dapiprazole hydrochloride
Drug Entry
Dapiprazole

Dapiprazole (U.S. trade name Rev-Eyes) is an alpha blocker. It is found in ophthalmic solutions used to reverse mydriasis after an eye examination.

Accession Number
DBSALT001438
Structure
Synonyms
Dapiprazole HCl
UNII
DS9UJN1I0X
CAS Number
72822-13-0
Weight
Average: 361.92
Monoisotopic: 361.2033236
Chemical Formula
C19H28ClN5
InChI Key
ZIODNPFQZIHCOE-UHFFFAOYSA-N
InChI
InChI=1S/C19H27N5.ClH/c1-16-6-2-3-7-17(16)23-14-12-22(13-15-23)11-9-19-21-20-18-8-4-5-10-24(18)19;/h2-3,6-7H,4-5,8-15H2,1H3;1H
IUPAC Name
1-(2-methylphenyl)-4-(2-{5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyridin-3-yl}ethyl)piperazine hydrochloride
SMILES
Cl.CC1=CC=CC=C1N1CCN(CCC2=NN=C3CCCCN23)CC1
ChemSpider
5293013
ChEMBL
CHEMBL1201044
Wikipedia
Dapiprazole
Predicted Properties
PropertyValueSource
Water Solubility0.751 mg/mLALOGPS
logP2.78ALOGPS
logP2.42Chemaxon
logS-2.6ALOGPS
pKa (Strongest Basic)7.67Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count4Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area37.19 Å2Chemaxon
Rotatable Bond Count4Chemaxon
Refractivity100.22 m3·mol-1Chemaxon
Polarizability37.6 Å3Chemaxon
Number of Rings4Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon