NAV

Chloramphenicol palmitate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Chloramphenicol palmitate
DrugBank Accession Number
DB14658
Background

Not Available

Type
Small Molecule
Groups
Approved, Vet approved
Structure
Similar Structures
Weight
Average: 561.54
Monoisotopic: 560.2419925
Chemical Formula
C27H42Cl2N2O6
Synonyms
  • CAP-palmitate
  • Chloramphenicol monopalmitate
  • Chloramphenicol palmitate
  • Detreopal
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
No interactions found.

Products

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International/Other Brands
Quemicetina

Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as nitrobenzenes. These are compounds containing a nitrobenzene moiety, which consists of a benzene ring with a carbon bearing a nitro group.
Kingdom
Organic compounds
Super Class
Benzenoids
Class
Benzene and substituted derivatives
Sub Class
Nitrobenzenes
Direct Parent
Nitrobenzenes
Alternative Parents
Nitroaromatic compounds / Fatty acid esters / Secondary carboxylic acid amides / Secondary alcohols / Carboxylic acid esters / Propargyl-type 1,3-dipolar organic compounds / Monocarboxylic acids and derivatives / Organic oxoazanium compounds / Organic oxides / Organic zwitterions
show 7 more
Substituents
Alcohol / Alkyl chloride / Alkyl halide / Allyl-type 1,3-dipolar organic compound / Aromatic alcohol / Aromatic homomonocyclic compound / C-nitro compound / Carbonyl group / Carboxamide group / Carboxylic acid derivative
show 22 more
Molecular Framework
Aromatic homomonocyclic compounds
External Descriptors
palmitate ester (CHEBI:3605)
Affected organisms
Not Available

Chemical Identifiers

UNII
43VU4207NW
CAS number
530-43-8
InChI Key
PXKHGMGELZGJQE-ILBGXUMGSA-N
InChI
InChI=1S/C27H42Cl2N2O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-24(32)37-20-23(30-27(34)26(28)29)25(33)21-16-18-22(19-17-21)31(35)36/h16-19,23,25-26,33H,2-15,20H2,1H3,(H,30,34)/t23-,25-/m1/s1
IUPAC Name
(2R,3R)-2-(2,2-dichloroacetamido)-3-hydroxy-3-(4-nitrophenyl)propyl hexadecanoate
SMILES
CCCCCCCCCCCCCCCC(=O)OC[C@@H](NC(=O)C(Cl)Cl)[C@H](O)C1=CC=C(C=C1)[N+]([O-])=O

References

General References
Not Available
KEGG Drug
D01072
KEGG Compound
C11726
ChemSpider
391613
ChEBI
3605
ChEMBL
CHEMBL1506
ZINC
ZINC000008214521
Wikipedia
Chloramphenicol

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
PowderNot applicable1 g/1g
Suspension
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility9.51e-05 mg/mLALOGPS
logP7.04ALOGPS
logP7.8Chemaxon
logS-6.8ALOGPS
pKa (Strongest Acidic)9.07Chemaxon
pKa (Strongest Basic)-3.4Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count5Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area118.77 Å2Chemaxon
Rotatable Bond Count22Chemaxon
Refractivity145.79 m3·mol-1Chemaxon
Polarizability61.7 Å3Chemaxon
Number of Rings1Chemaxon
Bioavailability0Chemaxon
Rule of FiveNoChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-222.96107
predicted
DeepCCS 1.0 (2019)
[M+H]+225.35664
predicted
DeepCCS 1.0 (2019)
[M+Na]+231.26917
predicted
DeepCCS 1.0 (2019)

Drug created at September 03, 2018 03:20 / Updated at September 28, 2021 21:55