Protokylol hydrochlorideProduct ingredient for Protokylol
- Name
- Protokylol hydrochloride
- Drug Entry
- Protokylol
Protokylol is a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States.
- Accession Number
- DBSALT001481
- Structure
Structure for Protokylol hydrochloride (DBSALT001481)
- Synonyms
- Protokylol HCl
- UNII
- 7U7O8Q48IO
- CAS Number
- 136-69-6
- Weight
- Average: 367.83
Monoisotopic: 367.1186505 - Chemical Formula
- C18H22ClNO5
- InChI Key
- LOVXREQUMZKFCM-UHFFFAOYSA-N
- InChI
- InChI=1S/C18H21NO5.ClH/c1-11(6-12-2-5-17-18(7-12)24-10-23-17)19-9-16(22)13-3-4-14(20)15(21)8-13;/h2-5,7-8,11,16,19-22H,6,9-10H2,1H3;1H
- IUPAC Name
- 4-(2-{[1-(2H-1,3-benzodioxol-5-yl)propan-2-yl]amino}-1-hydroxyethyl)benzene-1,2-diol hydrochloride
- SMILES
- Cl.CC(CC1=CC=C2OCOC2=C1)NCC(O)C1=CC=C(O)C(O)=C1
- External Links
- ChemSpider
- 8375
- BindingDB
- 50238665
- ChEMBL
- CHEMBL1200893
- Wikipedia
- Protokylol
- Predicted Properties
Property Value Source Water Solubility 0.236 mg/mL ALOGPS logP 1.29 ALOGPS logP 1.48 Chemaxon logS -3.2 ALOGPS pKa (Strongest Acidic) 9.86 Chemaxon pKa (Strongest Basic) 8.98 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 91.18 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 88.78 m3·mol-1 Chemaxon Polarizability 35.41 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon