Amobarbital sodiumProduct ingredient for Amobarbital
- Name
- Amobarbital sodium
- Drug Entry
- Amobarbital
A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
- Accession Number
- DBSALT001490
- Structure
- Synonyms
- Not Available
- UNII
- G0313KNC7D
- CAS Number
- 64-43-7
- Weight
- Average: 248.258
Monoisotopic: 248.1136867 - Chemical Formula
- C11H17N2NaO3
- InChI Key
- BNHGKKNINBGEQL-UHFFFAOYSA-M
- InChI
- InChI=1S/C11H18N2O3.Na/c1-4-11(6-5-7(2)3)8(14)12-10(16)13-9(11)15;/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16);/q;+1/p-1
- IUPAC Name
- sodium 5-ethyl-6-hydroxy-5-(3-methylbutyl)-2-oxo-2,5-dihydropyrimidin-4-olate
- SMILES
- [Na+].CCC1(CCC(C)C)C(O)=NC(=O)N=C1[O-]
- External Links
- ChemSpider
- 5917
- ChEMBL
- CHEMBL2105941
- Wikipedia
- Amobarbital
- Predicted Properties
Property Value Source Water Solubility 0.238 mg/mL ALOGPS logP 1.91 ALOGPS logP 2.63 Chemaxon logS -3 ALOGPS pKa (Strongest Acidic) 1.63 Chemaxon pKa (Strongest Basic) -4 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 85.08 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 69.2 m3·mol-1 Chemaxon Polarizability 23.02 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon