Atipamezole hydrochlorideProduct ingredient for Atipamezole
- Name
- Atipamezole hydrochloride
- Drug Entry
- Atipamezole
Atipamezole is a synthetic α2 adrenoceptor antagonistused to reverse the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs. It has also been undergone research as a potential anti-Parkinsonian drug for humans.
- Accession Number
- DBSALT001642
- Structure
Structure for Atipamezole hydrochloride (DBSALT001642)
- Synonyms
- Atipamezole HCl
- UNII
- 2W4279571X
- CAS Number
- 104075-48-1
- Weight
- Average: 248.75
Monoisotopic: 248.1080263 - Chemical Formula
- C14H17ClN2
- InChI Key
- PCCVCJAQMHDWJY-UHFFFAOYSA-N
- InChI
- InChI=1S/C14H16N2.ClH/c1-2-14(13-9-15-10-16-13)7-11-5-3-4-6-12(11)8-14;/h3-6,9-10H,2,7-8H2,1H3,(H,15,16);1H
- IUPAC Name
- 5-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole hydrochloride
- SMILES
- Cl.CCC1(CC2=C(C1)C=CC=C2)C1=CN=CN1
- External Links
- ChemSpider
- 13077441
- ChEMBL
- CHEMBL2361649
- Predicted Properties
Property Value Source Water Solubility 0.0706 mg/mL ALOGPS logP 3.32 ALOGPS logP 2.95 Chemaxon logS -3.5 ALOGPS pKa (Strongest Acidic) 13.33 Chemaxon pKa (Strongest Basic) 7.2 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 28.68 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 65.49 m3·mol-1 Chemaxon Polarizability 24.31 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon