Piperazine adipateProduct ingredient for Piperazine

Name
Piperazine adipate
Drug Entry
Piperazine

Piperazine is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms. First used as a solvent for uric acid, the use of piperazine as an anthelmintic agent was first introduced in 1953. Upon entry into the systemic circulation, the drug is partly oxidized and partly eliminated as an unchanged compound. Outside the body, piperazine has a remarkable power to dissolve uric acid and producing a soluble urate, but in clinical experience it has not proved equally successful. Piperazine was first introduced as an anthelmintic in 1953. Piperazine compounds mediate their anthelmintic action by generally paralyzing parasites, allowing the host body to easily remove or expel the invading organism.

Accession Number
DBSALT001654
Structure
Synonyms
Not Available
UNII
V7P5P122LB
CAS Number
142-88-1
Weight
Average: 232.28
Monoisotopic: 232.142307132
Chemical Formula
C10H20N2O4
InChI Key
BVEGEKOBSPXUJS-UHFFFAOYSA-N
InChI
InChI=1S/C6H10O4.C4H10N2/c7-5(8)3-1-2-4-6(9)10;1-2-6-4-3-5-1/h1-4H2,(H,7,8)(H,9,10);5-6H,1-4H2
IUPAC Name
hexanedioic acid; piperazine
SMILES
C1CNCCN1.OC(=O)CCCCC(O)=O
KEGG Compound
C13811
ChemSpider
8565
ChEBI
133924
ChEMBL
CHEMBL3276110
Predicted Properties
PropertyValueSource
Water Solubility32.2 mg/mLALOGPS
logP0.13ALOGPS
logP0.49Chemaxon
logS-0.66ALOGPS
pKa (Strongest Acidic)3.92Chemaxon
Physiological Charge-2Chemaxon
Hydrogen Acceptor Count4Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area74.6 Å2Chemaxon
Rotatable Bond Count5Chemaxon
Refractivity32.74 m3·mol-1Chemaxon
Polarizability14.24 Å3Chemaxon
Number of Rings1Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon