Detomidine hydrochlorideProduct ingredient for Detomidine
- Name
- Detomidine hydrochloride
- Drug Entry
- Detomidine
Detomidine is an α2-adrenergic agonist that is used as a horse sedative. Normally, it is administered in the salt form, detomidine hydrochloride. This drug is prescribed by veterinarians and is marketed as Dormosedan. Currently, it is only approved by the FDA for use in horses but has been studied for use in other large animals.
- Accession Number
- DBSALT001711
- Structure
Structure for Detomidine hydrochloride (DBSALT001711)
- Synonyms
- Detomidine HCl
- UNII
- 95K4LKB6QE
- CAS Number
- 90038-01-0
- Weight
- Average: 222.72
Monoisotopic: 222.0923762 - Chemical Formula
- C12H15ClN2
- InChI Key
- OIWRDXKNDCJZSM-UHFFFAOYSA-N
- InChI
- InChI=1S/C12H14N2.ClH/c1-9-4-3-5-11(10(9)2)6-12-7-13-8-14-12;/h3-5,7-8H,6H2,1-2H3,(H,13,14);1H
- IUPAC Name
- 4-[(2,3-dimethylphenyl)methyl]-1H-imidazole hydrochloride
- SMILES
- Cl.CC1=CC=CC(CC2=CNC=N2)=C1C
- External Links
- KEGG Drug
- D03702
- ChemSpider
- 50585
- ChEMBL
- CHEMBL2106210
- Predicted Properties
Property Value Source Water Solubility 0.658 mg/mL ALOGPS logP 2.79 ALOGPS logP 2.85 Chemaxon logS -2.4 ALOGPS pKa (Strongest Acidic) 14.2 Chemaxon pKa (Strongest Basic) 6.62 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 28.68 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 58.41 m3·mol-1 Chemaxon Polarizability 21.28 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon