Cefpodoxime sodiumProduct ingredient for Cefpodoxime
- Name
- Cefpodoxime sodium
- Drug Entry
- Cefpodoxime
Cefpodoxime is an oral third generation cephalosporin antibiotic with effectiveness against most Gram positive and Gram negative bacteria. Commonly used to treat acute otitis media, pharyngitis, and sinusitis, cefpodoxime proxetil is a prodrug which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime.
- Accession Number
- DBSALT001810
- Structure
Structure for Cefpodoxime sodium (DBSALT001810)
- Synonyms
- Not Available
- UNII
- 3ULP5169B3
- CAS Number
- 82619-04-3
- Weight
- Average: 449.43
Monoisotopic: 449.04396988 - Chemical Formula
- C15H16N5NaO6S2
- InChI Key
- JNMXSNGAMPXCDR-XYNKDNFRSA-M
- InChI
- InChI=1S/C15H17N5O6S2.Na/c1-25-3-6-4-27-13-9(12(22)20(13)10(6)14(23)24)18-11(21)8(19-26-2)7-5-28-15(16)17-7;/h5,9,13H,3-4H2,1-2H3,(H2,16,17)(H,18,21)(H,23,24);/q;+1/p-1/b19-8-;/t9-,13-;/m1./s1
- IUPAC Name
- sodium (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- SMILES
- [Na+].COCC1=C(N2[C@H](SC1)[C@H](NC(=O)C(=N/OC)\C1=CSC(N)=N1)C2=O)C([O-])=O
- External Links
- ChemSpider
- 7851231
- Predicted Properties
Property Value Source Water Solubility 0.228 mg/mL ALOGPS logP 0.8 ALOGPS logP -1.7 Chemaxon logS -3.3 ALOGPS pKa (Strongest Acidic) 3.22 Chemaxon pKa (Strongest Basic) 4.16 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 9 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 159.27 Å2 Chemaxon Rotatable Bond Count 7 Chemaxon Refractivity 111.55 m3·mol-1 Chemaxon Polarizability 39.94 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon