Citrated calcium carbimideProduct ingredient for Calcium carbimide
- Name
- Citrated calcium carbimide
- Drug Entry
- Calcium carbimide
Calcium carbimide, sold as the citrate salt, is an alcohol-sensitizing agent. Its effects are similar to the drug disulfiram (Antabuse) in that it interferes with the normal metabolism of alcohol by preventing the breakdown of the metabolic product acetaldehyde. Calcium carbimide was conceived as an alternative for the treatment of alcoholism with a reduced side effect profile either when it is consumed accompanied by alcohol or without it.1 This drug was developed by Lederle Cyanamid Canada Inc and approved for marketing in Canada in 1959. The current status of calcium carbimide is cancelled post marketing.8
- Accession Number
- DBSALT001860
- Structure
Structure for Citrated calcium carbimide (DBSALT001860)
- Synonyms
- 2-hydroxy-1,2,3-propanetricarboxylic acid mixt. with cyanamide calcium salt (1:1) / 2-hydroxy-1,2,3-propanetricarboxylic acid, cyanamide, calcium salt (1:1:1) Calcium cyanamide citrated
- UNII
- 21ZCD2AA4H
- CAS Number
- 8013-88-5
- Weight
- Average: 292.301
Monoisotopic: 292.0583418 - Chemical Formula
- C8H16CaN2O7
- InChI Key
- NEZBLMYXHFALIF-UHFFFAOYSA-N
- InChI
- InChI=1S/C6H8O7.C2H4N2.Ca.4H/c7-3(8)1-6(13,5(11)12)2-4(9)10;1-4-2-3;;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);4H,1H3;;;;;
- IUPAC Name
- 2-hydroxypropane-1,2,3-tricarboxylic acid cyano(methyl)amine calcium dihydride
- SMILES
- [H].[H].[CaH2].CNC#N.OC(=O)CC(O)(CC(O)=O)C(O)=O
- External Links
- Wikipedia
- Calcium_carbimide
- Predicted Properties
Property Value Source Water Solubility 106.0 mg/mL ALOGPS logP -1.3 ALOGPS logP -1.3 Chemaxon logS -0.26 ALOGPS pKa (Strongest Acidic) 3.05 Chemaxon pKa (Strongest Basic) -4.2 Chemaxon Physiological Charge -3 Chemaxon Hydrogen Acceptor Count 7 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 132.13 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 35.62 m3·mol-1 Chemaxon Polarizability 15.5 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon