Magnesium salicylate tetrahydrateProduct ingredient for Magnesium salicylate

Name
Magnesium salicylate tetrahydrate
Drug Entry
Magnesium salicylate

Magnesium salicylate is a non-steroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain. It is available in several over-the-counter (OTC) formulations. Though the recommended doseage is 1160 mg every six hours, per package directions of the Doan's OTC brand (580 mg magnesium salicylate tetrahydrate, equivalent to 934.4 mg anhydrous magnesium salicylate), effective pain relief is often found with a half dosage, with reduced anti-inflammatory results.

Accession Number
DBSALT001864
Structure
Thumb
Synonyms
Magnesium salicylate
UNII
41728CY7UX
CAS Number
18917-95-8
Weight
Average: 370.593
Monoisotopic: 370.07503848
Chemical Formula
C14H18MgO10
InChI Key
NBQBEWAYWAMLJJ-UHFFFAOYSA-L
InChI
InChI=1S/2C7H6O3.Mg.4H2O/c2*8-6-4-2-1-3-5(6)7(9)10;;;;;/h2*1-4,8H,(H,9,10);;4*1H2/q;;+2;;;;/p-2
IUPAC Name
magnesium(2+) bis(2-hydroxybenzoate) tetrahydrate
SMILES
O.O.O.O.[Mg++].OC1=CC=CC=C1C([O-])=O.OC1=CC=CC=C1C([O-])=O
ChemSpider
4445546
ChEMBL
CHEMBL3989810
Wikipedia
Magnesium_salicylate
Predicted Properties
PropertyValueSource
Water Solubility0.0686 mg/mLALOGPS
logP2.86ALOGPS
logP1.98ChemAxon
logS-3.6ALOGPS
pKa (Strongest Acidic)2.79ChemAxon
pKa (Strongest Basic)-6.3ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area60.36 Å2ChemAxon
Rotatable Bond Count2ChemAxon
Refractivity46.13 m3·mol-1ChemAxon
Polarizability12.38 Å3ChemAxon
Number of Rings2ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon