Hydroxyamfetamine hydrobromideProduct ingredient for Hydroxyamphetamine

Name
Hydroxyamfetamine hydrobromide
Drug Entry
Hydroxyamphetamine

Hydroxyamphetamine is a derivative of amphetamines. Hydroxyamphetamine is intended mainly as local eye drops for diagnostic purposes. It is indirect sympathomimetic agent which cause dilation of the eye pupil before diagnostic test. Among the minor side effects from its use are: change in color vision, difficulty seeing at night, dry mouth, headache, increased sensitivity of eyes to sunlight, muscle stiffness or tightness and temporary stinging in the eyes. The main use of hydroxyamphetamines as eye drops is the diagnosis of Horner's syndrome which is characterized by nerve lesions.

Accession Number
DBSALT001968
Structure
Thumb
Synonyms
Hydroxyamfetamine HBr / Hydroxyamphetamine HBr / Hydroxyamphetamine hydrobromide
UNII
59IG47SZ0E
CAS Number
306-21-8
Weight
Average: 232.121
Monoisotopic: 231.025877
Chemical Formula
C9H14BrNO
InChI Key
RZCJLMTXBMNRAD-UHFFFAOYSA-N
InChI
InChI=1S/C9H13NO.BrH/c1-7(10)6-8-2-4-9(11)5-3-8;/h2-5,7,11H,6,10H2,1H3;1H
IUPAC Name
4-(2-aminopropyl)phenol hydrobromide
SMILES
Br.CC(N)CC1=CC=C(O)C=C1
External Links
ChemSpider
9009
ChEMBL
CHEMBL1200705
Predicted Properties
PropertyValueSource
Water Solubility3.13 mg/mLALOGPS
logP0.58ALOGPS
logP1ChemAxon
logS-1.7ALOGPS
pKa (Strongest Acidic)10.48ChemAxon
pKa (Strongest Basic)9.8ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area46.25 Å2ChemAxon
Rotatable Bond Count2ChemAxon
Refractivity45.69 m3·mol-1ChemAxon
Polarizability17.17 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon