Hydroxyamfetamine hydrobromideProduct ingredient for Hydroxyamphetamine
- Name
- Hydroxyamfetamine hydrobromide
- Drug Entry
- Hydroxyamphetamine
Hydroxyamphetamine is a derivative of amphetamines. Hydroxyamphetamine is intended mainly as local eye drops for diagnostic purposes. It is indirect sympathomimetic agent which cause dilation of the eye pupil before diagnostic test. Among the minor side effects from its use are: change in color vision, difficulty seeing at night, dry mouth, headache, increased sensitivity of eyes to sunlight, muscle stiffness or tightness and temporary stinging in the eyes. The main use of hydroxyamphetamines as eye drops is the diagnosis of Horner's syndrome which is characterized by nerve lesions.
- Accession Number
- DBSALT001968
- Structure
- Synonyms
- Hydroxyamfetamine HBr / Hydroxyamphetamine HBr / Hydroxyamphetamine hydrobromide
- UNII
- 59IG47SZ0E
- CAS Number
- 306-21-8
- Weight
- Average: 232.121
Monoisotopic: 231.025877 - Chemical Formula
- C9H14BrNO
- InChI Key
- RZCJLMTXBMNRAD-UHFFFAOYSA-N
- InChI
- InChI=1S/C9H13NO.BrH/c1-7(10)6-8-2-4-9(11)5-3-8;/h2-5,7,11H,6,10H2,1H3;1H
- IUPAC Name
- 4-(2-aminopropyl)phenol hydrobromide
- SMILES
- Br.CC(N)CC1=CC=C(O)C=C1
- External Links
- ChemSpider
- 9009
- ChEMBL
- CHEMBL1200705
- Predicted Properties
Property Value Source Water Solubility 3.13 mg/mL ALOGPS logP 0.58 ALOGPS logP 1 Chemaxon logS -1.7 ALOGPS pKa (Strongest Acidic) 10.48 Chemaxon pKa (Strongest Basic) 9.8 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 46.25 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 45.69 m3·mol-1 Chemaxon Polarizability 17.17 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon