Encenicline hydrochlorideProduct ingredient for Encenicline
- Name
- Encenicline hydrochloride
- Drug Entry
- Encenicline
Encenicline has been investigated for the treatment of Cognition, Schizophrenia, Alzheimer's Disease, Cardiac Repolarization, and Central Nervous System Diseases.
- Accession Number
- DBSALT002058
- Structure
Structure for Encenicline hydrochloride (DBSALT002058)
- Synonyms
- Not Available
- UNII
- VYV1YE9W06
- CAS Number
- 550999-74-1
- Weight
- Average: 357.29
Monoisotopic: 356.0516898 - Chemical Formula
- C16H18Cl2N2OS
- InChI Key
- OIJYTJGIDVTCFF-ZOWNYOTGSA-N
- InChI
- InChI=1S/C16H17ClN2OS.ClH/c17-12-3-1-2-11-8-14(21-15(11)12)16(20)18-13-9-19-6-4-10(13)5-7-19;/h1-3,8,10,13H,4-7,9H2,(H,18,20);1H/t13-;/m0./s1
- IUPAC Name
- N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-7-chloro-1-benzothiophene-2-carboxamide hydrochloride
- SMILES
- Cl.ClC1=C2SC(=CC2=CC=C1)C(=O)N[C@H]1CN2CCC1CC2
- External Links
- ChemSpider
- 28637759
- ChEMBL
- CHEMBL3137323
- Wikipedia
- Encenicline
- Predicted Properties
Property Value Source Water Solubility 0.00872 mg/mL ALOGPS logP 3.33 ALOGPS logP 3.04 Chemaxon logS -4.6 ALOGPS pKa (Strongest Acidic) 14.42 Chemaxon pKa (Strongest Basic) 7.28 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 32.34 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 85.93 m3·mol-1 Chemaxon Polarizability 33.8 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon