Darexaban MaleateProduct ingredient for Darexaban
- Name
- Darexaban Maleate
- Drug Entry
- Darexaban
Darexaban has been used in trials studying the prevention and basic science of Japanese, Caucasian, Thromboembolism, Pharmacodynamics, and Pharmacokinetics, among others.
- Accession Number
- DBSALT002172
- Structure
Structure for Darexaban Maleate (DBSALT002172)
- Synonyms
- Not Available
- UNII
- 03RTP2436R
- CAS Number
- 365462-24-4
- Weight
- Average: 590.633
Monoisotopic: 590.237664071 - Chemical Formula
- C31H34N4O8
- InChI Key
- WHMPMUVISXATBH-BTJKTKAUSA-N
- InChI
- InChI=1S/C27H30N4O4.C4H4O4/c1-30-15-4-16-31(18-17-30)21-11-7-19(8-12-21)27(34)29-25-23(5-3-6-24(25)32)28-26(33)20-9-13-22(35-2)14-10-20;5-3(6)1-2-4(7)8/h3,5-14,32H,4,15-18H2,1-2H3,(H,28,33)(H,29,34);1-2H,(H,5,6)(H,7,8)/b;2-1-
- IUPAC Name
- (2Z)-but-2-enedioic acid; N-[2-hydroxy-6-(4-methoxybenzamido)phenyl]-4-(4-methyl-1,4-diazepan-1-yl)benzamide
- SMILES
- OC(=O)\C=C/C(O)=O.COC1=CC=C(C=C1)C(=O)NC1=C(NC(=O)C2=CC=C(C=C2)N2CCCN(C)CC2)C(O)=CC=C1
- External Links
- ChemSpider
- 28483601
- ChEMBL
- CHEMBL1922345
- Predicted Properties
Property Value Source Water Solubility 0.0291 mg/mL ALOGPS logP 4.03 ALOGPS logP 2.96 Chemaxon logS -4.2 ALOGPS pKa (Strongest Acidic) 8.32 Chemaxon pKa (Strongest Basic) 8.95 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 94.14 Å2 Chemaxon Rotatable Bond Count 8 Chemaxon Refractivity 140.91 m3·mol-1 Chemaxon Polarizability 52.34 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon