Dopexamine HydrochlorideProduct ingredient for Dopexamine
- Name
- Dopexamine Hydrochloride
- Drug Entry
- Dopexamine
Dopexamine has been used in trials studying the diagnostic and treatment of Free Flap, Oral Cancer, Hypotension, Septic Shock, and Head and Neck Cancer.
- Accession Number
- DBSALT002175
- Structure
Structure for Dopexamine Hydrochloride (DBSALT002175)
- Synonyms
- Not Available
- UNII
- 0VN909S60Y
- CAS Number
- 86484-91-5
- Weight
- Average: 429.43
Monoisotopic: 428.1997337 - Chemical Formula
- C22H34Cl2N2O2
- InChI Key
- VPDULUNRSQWWJB-UHFFFAOYSA-N
- InChI
- InChI=1S/C22H32N2O2.2ClH/c25-21-11-10-20(18-22(21)26)13-17-24-15-7-2-1-6-14-23-16-12-19-8-4-3-5-9-19;;/h3-5,8-11,18,23-26H,1-2,6-7,12-17H2;2*1H
- IUPAC Name
- 4-[2-({6-[(2-phenylethyl)amino]hexyl}amino)ethyl]benzene-1,2-diol dihydrochloride
- SMILES
- Cl.Cl.OC1=CC=C(CCNCCCCCCNCCC2=CC=CC=C2)C=C1O
- External Links
- ChemSpider
- 61869
- ChEMBL
- CHEMBL3989581
- Predicted Properties
Property Value Source Water Solubility 0.00243 mg/mL ALOGPS logP 3.75 ALOGPS logP 2.98 Chemaxon logS -5.2 ALOGPS pKa (Strongest Acidic) 10.71 Chemaxon pKa (Strongest Basic) 10.14 Chemaxon Physiological Charge 2 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 64.52 Å2 Chemaxon Rotatable Bond Count 13 Chemaxon Refractivity 108.83 m3·mol-1 Chemaxon Polarizability 43.8 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon