Radezolid hydrochlorideProduct ingredient for Radezolid
- Name
- Radezolid hydrochloride
- Drug Entry
- Radezolid
Radezolid has been used in trials studying the treatment of Abscess, Bacterial Skin Diseases, Streptococcal Infections, Infectious Skin Diseases, and Staphylococcal Skin Infections, among others.
- Accession Number
- DBSALT002178
- Structure
Structure for Radezolid hydrochloride (DBSALT002178)
- Synonyms
- Radezolid HCl
- External IDs
- RX-01 / RX-1741_667 / RX-1741667
- UNII
- 37CW568NXL
- CAS Number
- 869884-77-5
- Weight
- Average: 474.92
Monoisotopic: 474.1582445 - Chemical Formula
- C22H24ClFN6O3
- InChI Key
- UQKABVKLBIJYBI-FYZYNONXSA-N
- InChI
- InChI=1S/C22H23FN6O3.ClH/c1-14(30)25-12-19-13-29(22(31)32-19)18-6-7-20(21(23)8-18)16-4-2-15(3-5-16)9-24-10-17-11-26-28-27-17;/h2-8,11,19,24H,9-10,12-13H2,1H3,(H,25,30)(H,26,27,28);1H/t19-;/m0./s1
- IUPAC Name
- N-{[(5S)-3-[2-fluoro-4'-({[(1H-1,2,3-triazol-5-yl)methyl]amino}methyl)-[1,1'-biphenyl]-4-yl]-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide hydrochloride
- SMILES
- Cl.CC(=O)NC[C@H]1CN(C(=O)O1)C1=CC=C(C(F)=C1)C1=CC=C(CNCC2=CN=NN2)C=C1
- External Links
- ChemSpider
- 28530506
- ChEMBL
- CHEMBL2105651
- Predicted Properties
Property Value Source Water Solubility 0.043 mg/mL ALOGPS logP 1.23 ALOGPS logP 1.29 Chemaxon logS -4 ALOGPS pKa (Strongest Acidic) 8.56 Chemaxon pKa (Strongest Basic) 7.46 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 112.24 Å2 Chemaxon Rotatable Bond Count 8 Chemaxon Refractivity 115.89 m3·mol-1 Chemaxon Polarizability 45.2 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon