Procaine phosphateProduct ingredient for Procaine
- Name
- Procaine phosphate
- Drug Entry
- Procaine
A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in treatment-experienced HIV patients 2.
- Accession Number
- DBSALT002215
- Structure
Structure for Procaine phosphate (DBSALT002215)
- Synonyms
- Not Available
- UNII
- A18LHT9ZXJ
- CAS Number
- 54812-66-7
- Weight
- Average: 334.309
Monoisotopic: 334.129373467 - Chemical Formula
- C13H23N2O6P
- InChI Key
- NPBISBZNYVWJOL-UHFFFAOYSA-N
- InChI
- InChI=1S/C13H20N2O2.H3O4P/c1-3-15(4-2)9-10-17-13(16)11-5-7-12(14)8-6-11;1-5(2,3)4/h5-8H,3-4,9-10,14H2,1-2H3;(H3,1,2,3,4)
- IUPAC Name
- 2-(diethylamino)ethyl 4-aminobenzoate; phosphoric acid
- SMILES
- OP(O)(O)=O.CCN(CC)CCOC(=O)C1=CC=C(N)C=C1
- External Links
- ChemSpider
- 202785
- Predicted Properties
Property Value Source Water Solubility 6.81 mg/mL ALOGPS logP 2.1 ALOGPS logP 1.88 Chemaxon logS -1.5 ALOGPS pKa (Strongest Basic) 8.96 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 55.56 Å2 Chemaxon Rotatable Bond Count 7 Chemaxon Refractivity 70.3 m3·mol-1 Chemaxon Polarizability 27.32 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon