Icosapent sodiumProduct ingredient for Icosapent
- Name
- Icosapent sodium
- Drug Entry
- Icosapent
Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families.
- Accession Number
- DBSALT002305
- Structure
Structure for Icosapent sodium (DBSALT002305)
- Synonyms
- Not Available
- UNII
- 5PXN91KPRO
- CAS Number
- 73167-03-0
- Weight
- Average: 324.44
Monoisotopic: 324.20652445 - Chemical Formula
- C20H29NaO2
- InChI Key
- RBZYGQJEMWGTOH-RSDXMDNYSA-M
- InChI
- InChI=1S/C20H30O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22;/h3-4,6-7,9-10,12-13,15-16H,2,5,8,11,14,17-19H2,1H3,(H,21,22);/q;+1/p-1/b4-3-,7-6-,10-9-,13-12-,16-15-;
- IUPAC Name
- sodium (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoate
- SMILES
- [Na+].CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC([O-])=O
- External Links
- ChemSpider
- 7994441
- Predicted Properties
Property Value Source Water Solubility 0.000247 mg/mL ALOGPS logP 6.49 ALOGPS logP 6.23 Chemaxon logS -6.1 ALOGPS pKa (Strongest Acidic) 4.82 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 40.13 Å2 Chemaxon Rotatable Bond Count 13 Chemaxon Refractivity 111.91 m3·mol-1 Chemaxon Polarizability 35.35 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon