Ribostamycin sulfateProduct ingredient for Ribostamycin
- Name
- Ribostamycin sulfate
- Drug Entry
- Ribostamycin
Ribostamycin is an aminoglycoside antibiotic1 isolated from Streptomyces ribosidificus2 listed as one of the World Health Organization's critically important antimicrobials.3
- Accession Number
- DBSALT002372
- Structure
Structure for Ribostamycin sulfate (DBSALT002372)
- Synonyms
- Vistamycin sulfate
- UNII
- QFN1QU7PEN
- CAS Number
- 53797-35-6
- Weight
- Average: 552.55
Monoisotopic: 552.194873029 - Chemical Formula
- C17H36N4O14S
- InChI Key
- RTCDDYYZMGGHOE-YMSVYGIHSA-N
- InChI
- InChI=1S/C17H34N4O10.H2O4S/c18-2-6-10(24)12(26)8(21)16(28-6)30-14-5(20)1-4(19)9(23)15(14)31-17-13(27)11(25)7(3-22)29-17;1-5(2,3)4/h4-17,22-27H,1-3,18-21H2;(H2,1,2,3,4)/t4-,5+,6-,7-,8-,9+,10-,11-,12-,13-,14-,15-,16-,17+;/m1./s1
- IUPAC Name
- (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2R,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy}oxane-3,4-diol; sulfuric acid
- SMILES
- OS(O)(=O)=O.NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)[C@H]2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)[C@H](N)[C@@H](O)[C@@H]1O
- External Links
- ChemSpider
- 571117
- ChEMBL
- CHEMBL3138633
- Predicted Properties
Property Value Source Water Solubility 88.7 mg/mL ALOGPS logP -2.9 ALOGPS logP -6.4 Chemaxon logS -0.71 ALOGPS pKa (Strongest Acidic) 12.19 Chemaxon pKa (Strongest Basic) 9.67 Chemaxon Physiological Charge 4 Chemaxon Hydrogen Acceptor Count 14 Chemaxon Hydrogen Donor Count 10 Chemaxon Polar Surface Area 262.38 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 100.17 m3·mol-1 Chemaxon Polarizability 44.29 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon