Fonazine mesylateProduct ingredient for Dimetotiazine

Name
Fonazine mesylate
Drug Entry
Dimetotiazine

Dimetotiazine has considerable antiemetic & serotonin antagonistic action used mainly in allergic skin conditions.

Accession Number
DBSALT002448
Structure
Thumb
Synonyms
Not Available
UNII
B28V86NGNK
CAS Number
13115-40-7
Weight
Average: 487.656
Monoisotopic: 487.126933123
Chemical Formula
C20H29N3O5S3
InChI Key
JGKVKXPDDVRUKC-UHFFFAOYSA-N
InChI
InChI=1S/C19H25N3O2S2.CH4O3S/c1-14(20(2)3)13-22-16-8-6-7-9-18(16)25-19-11-10-15(12-17(19)22)26(23,24)21(4)5;1-5(2,3)4/h6-12,14H,13H2,1-5H3;1H3,(H,2,3,4)
IUPAC Name
10-[2-(dimethylamino)propyl]-N,N-dimethyl-10H-phenothiazine-2-sulfonamide; methanesulfonic acid
SMILES
CS(O)(=O)=O.CC(CN1C2=CC=CC=C2SC2=C1C=C(C=C2)S(=O)(=O)N(C)C)N(C)C
External Links
ChemSpider
23956
ChEBI
31499
ChEMBL
CHEMBL2104669
Predicted Properties
PropertyValueSource
Water Solubility0.0647 mg/mLALOGPS
logP3.47ALOGPS
logP3.34ChemAxon
logS-3.8ALOGPS
pKa (Strongest Basic)8.99ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count4ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area43.86 Å2ChemAxon
Rotatable Bond Count4ChemAxon
Refractivity110.46 m3·mol-1ChemAxon
Polarizability41.79 Å3ChemAxon
Number of Rings3ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon