Fonazine mesylateProduct ingredient for Dimetotiazine
- Name
- Fonazine mesylate
- Drug Entry
- Dimetotiazine
Dimetotiazine has considerable antiemetic & serotonin antagonistic action used mainly in allergic skin conditions.
- Accession Number
- DBSALT002448
- Structure
Structure for Fonazine mesylate (DBSALT002448)
- Synonyms
- Not Available
- UNII
- B28V86NGNK
- CAS Number
- 13115-40-7
- Weight
- Average: 487.656
Monoisotopic: 487.126933123 - Chemical Formula
- C20H29N3O5S3
- InChI Key
- JGKVKXPDDVRUKC-UHFFFAOYSA-N
- InChI
- InChI=1S/C19H25N3O2S2.CH4O3S/c1-14(20(2)3)13-22-16-8-6-7-9-18(16)25-19-11-10-15(12-17(19)22)26(23,24)21(4)5;1-5(2,3)4/h6-12,14H,13H2,1-5H3;1H3,(H,2,3,4)
- IUPAC Name
- 10-[2-(dimethylamino)propyl]-N,N-dimethyl-10H-phenothiazine-2-sulfonamide; methanesulfonic acid
- SMILES
- CS(O)(=O)=O.CC(CN1C2=CC=CC=C2SC2=C1C=C(C=C2)S(=O)(=O)N(C)C)N(C)C
- External Links
- ChemSpider
- 23956
- ChEBI
- 31499
- ChEMBL
- CHEMBL2104669
- Predicted Properties
Property Value Source Water Solubility 0.0647 mg/mL ALOGPS logP 3.47 ALOGPS logP 3.34 Chemaxon logS -3.8 ALOGPS pKa (Strongest Basic) 8.99 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 43.86 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 110.46 m3·mol-1 Chemaxon Polarizability 41.79 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon