Pimagedine hydrochlorideProduct ingredient for Pimagedine

Name
Pimagedine hydrochloride
Drug Entry
Pimagedine

Pimagedine has been developed by Synvista Therapeutics, Inc for the treatment of diabetic kidney disease. It is an advanced glycation end product inhibitor which manages diabetic nephropathy, either alone or in combination with other therapies. It is beneficial in treating patients with diabetic nephropathy.

Accession Number
DBSALT002490
Structure
Thumb
Synonyms
Aminoguanidine HCl / Aminoguanidine hydrochloride / Aminoguanidine monohydrochloride / Pimagedine HCl
UNII
A2Z7G2RGAH
CAS Number
1937-19-5
Weight
Average: 110.546
Monoisotopic: 110.035923951
Chemical Formula
CH7ClN4
InChI Key
UBDZFAGVPPMTIT-UHFFFAOYSA-N
InChI
InChI=1S/CH6N4.ClH/c2-1(3)5-4;/h4H2,(H4,2,3,5);1H
IUPAC Name
2-azaniumylguanidine chloride
SMILES
[Cl-].NC(N)=N[NH3+]
External Links
ChemSpider
15211
ChEMBL
CHEMBL1256292
Predicted Properties
PropertyValueSource
Water Solubility32.8 mg/mLALOGPS
logP-1.7ALOGPS
logP-1.5ChemAxon
logS-0.53ALOGPS
pKa (Strongest Basic)10.77ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count3ChemAxon
Polar Surface Area92.04 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity30.16 m3·mol-1ChemAxon
Polarizability7.32 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon