Sodium thiosulfate pentahydrateProduct ingredient for Thiosulfuric acid

Name
Sodium thiosulfate pentahydrate
Drug Entry
Thiosulfuric acid

Thiosulfuric acid (as sodium thiosulfate) has the chemical name thiosulfuric acid, disodium salt, pentahydrate. The chemical formula is Na2S2O3•5H2O and the molecular weight is 248.17. Sodium Thiosulfate Injection is a cyanide antidote which contains one 50 mL glass vial containing a 25% solution of Sodium Thiosulfate Injection.

It has been indicated as antidote for cyanide poisoning. It is also used as adjunct agent for patients taking cisplatin chemotherapy.

Beside the above indications, sodium thiosulfate could be used as ingredient in the following: agricultural chemicals (non-pesticidal), fillers, intermediates, laboratory chemicals, oxidizing/reducing agents, process regulators, processing aids, and solids separation agents.

Accession Number
DBSALT002505
Structure
Thumb
Synonyms
Sodium thiosulfate / Sodium thiosulfate hydrate
UNII
HX1032V43M
CAS Number
10102-17-7
Weight
Average: 248.17
Monoisotopic: 247.96124819
Chemical Formula
H10Na2O8S2
InChI Key
PODWXQQNRWNDGD-UHFFFAOYSA-L
InChI
InChI=1S/2Na.H2O3S2.5H2O/c;;1-5(2,3)4;;;;;/h;;(H2,1,2,3,4);5*1H2/q2*+1;;;;;;/p-2
IUPAC Name
disodium 1-oxo-1λ⁶-disulfene-1,1-bis(olate) pentahydrate
SMILES
O.O.O.O.O.[Na+].[Na+].[O-]S([O-])(=O)=S
External Links
ChemSpider
55396
ChEBI
32150
ChEMBL
CHEMBL2096650
Predicted Properties
PropertyValueSource
logP0.048ChemAxon
pKa (Strongest Acidic)2.7ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area63.19 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity19.52 m3·mol-1ChemAxon
Polarizability7.76 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon