Prifinium bromideProduct ingredient for Prifinium

Name
Prifinium bromide
Drug Entry
Prifinium

Prifinium is an antimuscarinic agent with antispasmodic and antiemetic properties. It may be useful for the treatment of irritable bowel syndrome 1.

Accession Number
DBSALT002516
Structure
Synonyms
Bromuro de prifinio / Prifinii bromidum / Prifinium bromide
UNII
3B7O9ZC520
CAS Number
4630-95-9
Weight
Average: 386.377
Monoisotopic: 385.140513
Chemical Formula
C22H28BrN
InChI Key
UCGJZJXOPSNTGZ-UHFFFAOYSA-M
InChI
InChI=1S/C22H28N.BrH/c1-4-23(5-2)17-16-21(18(23)3)22(19-12-8-6-9-13-19)20-14-10-7-11-15-20;/h6-15,18H,4-5,16-17H2,1-3H3;1H/q+1;/p-1
IUPAC Name
3-(diphenylmethylidene)-1,1-diethyl-2-methylpyrrolidin-1-ium bromide
SMILES
[Br-].CC[N+]1(CC)CCC(C1C)=C(C1=CC=CC=C1)C1=CC=CC=C1
KEGG Compound
C12814
ChemSpider
19537
ChEBI
32052
ChEMBL
CHEMBL1213353
Wikipedia
Prifinium_bromide
Predicted Properties
PropertyValueSource
Water Solubility7.22e-05 mg/mLALOGPS
logP2.13ALOGPS
logP0.7Chemaxon
logS-6.7ALOGPS
Physiological Charge1Chemaxon
Hydrogen Acceptor Count0Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area0 Å2Chemaxon
Rotatable Bond Count4Chemaxon
Refractivity120.85 m3·mol-1Chemaxon
Polarizability37.23 Å3Chemaxon
Number of Rings3Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon