Samarium (153Sm) lexidronam pentasodiumProduct ingredient for Samarium (153Sm) lexidronam

Name
Samarium (153Sm) lexidronam pentasodium
Drug Entry
Samarium (153Sm) lexidronam

Samarium Sm 153 lexidronam is a radioactive medication used to treat pain caused by cancer that has spread to the bone. It is a radiopharmaceutical. Radiopharmaceuticals are radioactive agents that may be used to diagnose some diseases by studying the function of the body's organs or to treat certain diseases.Samarium Sm 153 lexidronam is used to help relieve the bone pain that may occur with certain kinds of cancer. The radioactive samarium is taken up in the bone cancer area and gives off radiation that helps provide relief of pain.

Accession Number
DBSALT002635  (DB09509)
Structure
Thumb
Synonyms
Samarium (153 Sm) lexidronam pentasodium / Samarium [153Sm] lexidronam pentasodium / Samarium Sm 153 lexidronam pentasodium / Samarium Sm 153 lexidronam pentasodium salt / Samarium Sm153 lexidronam pentasodium / Sm-153 EDTMP pentasodium
External IDs
CYT 424 / CYT-124
UNII
7389YR3OOV
CAS Number
176669-18-4
Weight
Average: 695.93
Monoisotopic: 695.80501213
Chemical Formula
C6H12N2Na5O12P4Sm
InChI Key
SZZACTGRBZTAKY-NKNBZPHVSA-F
InChI
InChI=1S/C6H20N2O12P4.5Na.Sm/c9-21(10,11)3-7(4-22(12,13)14)1-2-8(5-23(15,16)17)6-24(18,19)20;;;;;;/h1-6H2,(H2,9,10,11)(H2,12,13,14)(H2,15,16,17)(H2,18,19,20);;;;;;/q;5*+1;+3/p-8/i;;;;;;1+3
IUPAC Name
(153Sm)samarium(3+) pentasodium [({2-[bis(phosphonomethyl)amino]ethyl}(phosphonomethyl)amino)methyl]phosphonate
SMILES
[Na+].[Na+].[Na+].[Na+].[Na+].[153Sm+3].[O-]P([O-])(=O)CN(CCN(CP([O-])([O-])=O)CP([O-])([O-])=O)CP([O-])([O-])=O
External Links
PubChem Compound
9810246
PubChem Substance
347827868
ChemSpider
7986002
Predicted Properties
PropertyValueSource
Water Solubility28.3 mg/mLALOGPS
logP0.96ALOGPS
logP-4.2ChemAxon
logS-1.4ALOGPS
pKa (Strongest Acidic)0.96ChemAxon
Physiological Charge-5ChemAxon
Hydrogen Acceptor Count14ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area259.24 Å2ChemAxon
Rotatable Bond Count11ChemAxon
Refractivity71.34 m3·mol-1ChemAxon
Polarizability30 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability0ChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon