Clinafloxacin hydrochlorideProduct ingredient for Clinafloxacin
- Name
- Clinafloxacin hydrochloride
- Drug Entry
- Clinafloxacin
Clinafloxacin is a fluoroquinolone antibacterial currently under research. It has been proven to present good antibiotic properties. However, its approval and release have been halted due to the presence of serious side effects.
- Accession Number
- DBSALT002698
- Structure
- Synonyms
- Clinafloxacin HCl
- UNII
- G17M59V0FY
- CAS Number
- 105956-99-8
- Weight
- Average: 402.25
Monoisotopic: 401.070925 - Chemical Formula
- C17H18Cl2FN3O3
- InChI Key
- BMACYHMTJHBPOX-UHFFFAOYSA-N
- InChI
- InChI=1S/C17H17ClFN3O3.ClH/c18-13-14-10(5-12(19)15(13)21-4-3-8(20)6-21)16(23)11(17(24)25)7-22(14)9-1-2-9;/h5,7-9H,1-4,6,20H2,(H,24,25);1H
- IUPAC Name
- 7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
- SMILES
- Cl.NC1CCN(C1)C1=C(F)C=C2C(=O)C(=CN(C3CC3)C2=C1Cl)C(O)=O
- External Links
- ChemSpider
- 54183
- ChEMBL
- CHEMBL537626
- Predicted Properties
Property Value Source Water Solubility 0.445 mg/mL ALOGPS logP 0.36 ALOGPS logP -0.42 Chemaxon logS -2.9 ALOGPS pKa (Strongest Acidic) 5.45 Chemaxon pKa (Strongest Basic) 9.63 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 86.87 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 92.51 m3·mol-1 Chemaxon Polarizability 35.67 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon