Englitazone sodiumProduct ingredient for Englitazone
- Name
- Englitazone sodium
- Drug Entry
- Englitazone
Englitazone is a hypoglycemic agent.
- Accession Number
- DBSALT002702
- Structure
Structure for Englitazone sodium (DBSALT002702)
- Synonyms
- Not Available
- External IDs
- CP-72,467-2 / CP-72467-2
- UNII
- VA5755GIJ8
- CAS Number
- 109229-57-4
- Weight
- Average: 375.42
Monoisotopic: 375.0905089 - Chemical Formula
- C20H18NNaO3S
- InChI Key
- JQWYNJRCVYGLMO-GPPXSFHXSA-M
- InChI
- InChI=1S/C20H19NO3S.Na/c22-19-18(25-20(23)21-19)12-14-6-9-17-15(10-14)7-8-16(24-17)11-13-4-2-1-3-5-13;/h1-6,9-10,16,18H,7-8,11-12H2,(H,21,22,23);/q;+1/p-1/t16-,18?;/m1./s1
- IUPAC Name
- sodium 5-{[(2R)-2-benzyl-3,4-dihydro-2H-1-benzopyran-6-yl]methyl}-2-oxo-2,5-dihydro-1,3-thiazol-4-olate
- SMILES
- [Na+].[H]C1(CC2=CC3=C(O[C@@]([H])(CC4=CC=CC=C4)CC3)C=C2)SC(=O)N=C1[O-]
- External Links
- ChemSpider
- 5293363
- ChEMBL
- CHEMBL3989578
- Predicted Properties
Property Value Source Water Solubility 0.000686 mg/mL ALOGPS logP 4.58 ALOGPS logP 4.71 Chemaxon logS -5.7 ALOGPS pKa (Strongest Acidic) 4.3 Chemaxon pKa (Strongest Basic) -4.3 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 61.72 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 108.94 m3·mol-1 Chemaxon Polarizability 36.63 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon