Edrophonium bromideProduct ingredient for Edrophonium
- Name
- Edrophonium bromide
- Drug Entry
- Edrophonium
A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
- Accession Number
- DBSALT002779
- Structure
Structure for Edrophonium bromide (DBSALT002779)
- Synonyms
- Not Available
- UNII
- KX008093VW
- CAS Number
- 302-83-0
- Weight
- Average: 246.148
Monoisotopic: 245.041527 - Chemical Formula
- C10H16BrNO
- InChI Key
- CAEPIUXAUPYIIJ-UHFFFAOYSA-N
- InChI
- InChI=1S/C10H15NO.BrH/c1-4-11(2,3)9-6-5-7-10(12)8-9;/h5-8H,4H2,1-3H3;1H
- IUPAC Name
- N-ethyl-3-hydroxy-N,N-dimethylanilinium bromide
- SMILES
- [Br-].CC[N+](C)(C)C1=CC=CC(O)=C1
- External Links
- ChemSpider
- 8972
- ChEMBL
- CHEMBL60745
- Predicted Properties
Property Value Source Water Solubility 0.0225 mg/mL ALOGPS logP -1.9 ALOGPS logP -1.9 Chemaxon logS -4 ALOGPS pKa (Strongest Acidic) 8.59 Chemaxon pKa (Strongest Basic) -6.1 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 20.23 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 62.41 m3·mol-1 Chemaxon Polarizability 19.15 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon