Ketobemidone oxalateProduct ingredient for Ketobemidone
- Name
- Ketobemidone oxalate
- Drug Entry
- Ketobemidone
Ketobemidone is a powerful opioid analgesic. It also has some NMDA-antagonist properties. This makes it useful for some types of pain that don't respond well to other opioids. The most commonly cited equalisation ratio for analgesic doses is 25 mg of ketobemidone hydrobromide to 60 mg of morphine hydrochloride or sulfate and circa 8 mg of ketobemidone by injection.
- Accession Number
- DBSALT002789
- Structure
Structure for Ketobemidone oxalate (DBSALT002789)
- Synonyms
- Not Available
- UNII
- Not Available
- CAS Number
- Not Available
- Weight
- Average: 337.372
Monoisotopic: 337.152537465 - Chemical Formula
- C17H23NO6
- InChI Key
- OPKJKUCDOASCBQ-UHFFFAOYSA-N
- InChI
- InChI=1S/C15H21NO2.C2H2O4/c1-3-14(18)15(7-9-16(2)10-8-15)12-5-4-6-13(17)11-12;3-1(4)2(5)6/h4-6,11,17H,3,7-10H2,1-2H3;(H,3,4)(H,5,6)
- IUPAC Name
- 1-[4-(3-hydroxyphenyl)-1-methylpiperidin-4-yl]propan-1-one; oxalic acid
- SMILES
- OC(=O)C(O)=O.CCC(=O)C1(CCN(C)CC1)C1=CC(O)=CC=C1
- External Links
- ChemSpider
- 23316260
- ChEMBL
- CHEMBL259124
- Predicted Properties
Property Value Source Water Solubility 3.01 mg/mL ALOGPS logP 2.01 ALOGPS logP 2.49 Chemaxon logS -1.9 ALOGPS pKa (Strongest Acidic) 9.44 Chemaxon pKa (Strongest Basic) 8.09 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 40.54 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 73.12 m3·mol-1 Chemaxon Polarizability 28.09 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon