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The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
Approved
Vet approved
Naloxone is an opioid antagonist medication used to block or reverse the effects of opioid drugs, particularly within the setting of drug overdoses which are rapidly becoming a leading cause of death worldwide. More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist,...
Approved
Vet approved
Matched Description: … [cocaine], or benzodiazepines like [lorazepam] or [diazepam]. ... subcutaneous (SubQ) injection, nasal spray, or intravenous (IV) infusion. ... Naloxone is an opioid antagonist medication used to block or reverse the effects of opioid drugs, particularly …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
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