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Coagulation factor VII is human serine protease type enzyme that is involved in the extrinsic coagulation cascade which results in blood clotting.
Approved
Investigational
Matched Synonyms: … Coagulation factor VII (human) ... Human coagulation factor VII ... Factor VII human
Matched Name: … Coagulation factor VII human
Matched Description: … Coagulation factor VII is human serine protease type enzyme that is involved in the extrinsic coagulation
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … coagulation factor IX, II, VII and X in combination ... coagulation factor VII ... Protein Precursors ... Enzymes and Coenzymes ... Blood Coagulation Factors …
Matched Products: … CONCENTRADO DE FACTOR VII ... Faktor VII "Takeda" 600 I.E. Pulver und Lösungsmittel zur Herstellung einer Injektionslösung …
Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Approved
Matched Synonyms: … Coagulation factor VIIa ... Coagulation factor VIIa (recombinant) ... Coagulation factor VIIa (recombinant)-jncw …
Matched Name: … Coagulation factor VIIa Recombinant Human
Matched Description: … Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the ... Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form ... extrinsic pathway of the coagulation cascade. …
Matched Categories: … Increased Coagulation Factor X Activity ... Increased Coagulation Factor IX Activity ... Factor VII ... coagulation factor VIIa ... Enzymes and Coenzymes …
Matched Products: … powder and solvent for solution for injection 2mg ... powder and solvent for solution for injection 1mg ... NOVOSEVEN 2MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and children (aged 12 years and above) with hereditary Factor X deficiency. However its use is limited in the perioperative setting for the management of bleeding in major surgery in patients with moderate and severe...
Approved
Investigational
Matched Synonyms: … Coagulation factor X (human) ... Human coagulation factor X ... Coagulation factor X
Matched Name: … Coagulation factor X human
Matched Description: … Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and ... Coagulation Factor X (Human) solution is approved by the FDA for intravenous injection under the market ... Administration of coagulation Factor X from healthy donor serves to restore and achieve effective hemostasis …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … coagulation factor X ... Factor X ... Factor X, agonists ... Protein Precursors ... Enzymes and Coenzymes …
Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) and purified from extraneous plasma-derived...
Approved
Matched Synonyms: … Human coagulation factor VIII ... F8 protein, human ... factor VIII, human
Matched Name: … Antihemophilic factor human
Matched Description: … Activation of Factor IX leads to a cascade of signals that results in activation of Factor X, which then ... a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential ... Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is …
Matched Mixtures name: … von Willebrand Factor/Coagulation Factor VIII Complex (Human) ... von Willebrand Factor/Coagulation Factor VIII Complex (Human) ... Wilate - von Willebrand Factor/Coagulation Factor VIII Complex (Human) …
Matched Categories: … coagulation factor VIII ... Protein Precursors ... Human Antihemophilic Factors ... Factor VIII ... Blood and Blood Forming Organs …
Matched Products: … Hyate C Inj Vial ... FACTOR VIII 500 IU FLAKON, 1 ADET ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. Also known as prothrombin complex concentrate, products containing this complex often include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and low levels of...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX, II, VII and X in combination ... Coagulation factor IX complex human ... Factor IX complex human
Matched Name: … Factor IX Complex (Human) …
Matched Description: … IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and low levels ... For example, Kcentra (FDA) also contains the antithrombotic proteins C and S, while Bebulin VH (FDA) ... of Factor VII (proconvertin) derived from human plasma. …
Matched Categories: … Factor IX ... Protein Precursors ... Blood Coagulation Factors ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Prothrombin Complex Concentrate (Human), is indicated for the urgent reversal of acquired coagulation factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients with acute major bleeding.
Approved
Matched Synonyms: … Coagulation factor II human ... Coagulation factor II (human) ... Human coagulation factor II …
Matched Name: … Prothrombin
Matched Description: … Prothrombin Complex Concentrate (Human), is indicated for the urgent reversal of acquired coagulation ... factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients with …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Protein Precursors ... Prothrombin, agonists ... Enzymes and Coenzymes ... Blood Coagulation Factors ... Amino Acids, Peptides, and Proteins …
Efmoroctocog alfa is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life compared with conventional factor VIII (FVIII) preparations, including recombinant FVIII (rFVIII) products such as DB13999 . It is an antihemorrhagic agent used in replacement therapy for patients with haemophilia A (congenital factor VIII deficiency). It...
Approved
Investigational
Matched Synonyms: … Coagulation factor VIII recombinant immunoglubulin g1 fusion protein ... Antihemophilic factor (recombinant, FC fusion protein) ... Antihemophilic Factor (Recombinant BDD), FC Fusion Protein
Matched Description: … is purified endogenous Factor VIII from human pooled blood and contains both A- and B-subunits. ... Efmoroctocog alfa is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life ... G1, a long-lived plasma protein [FDA Label]. …
Matched Categories: … Human Antihemophilic Factors …
Also known as coagulation factor II, thrombin is a serine protease that plays a physiological role in regulating hemostasis and maintaining blood coagulation. Once converted from prothrombin, thrombin converts fibrinogen to fibrin, which, in combination with platelets from the blood, forms a clot. Medical thrombin is a protein substance produced...
Approved
Investigational
Matched Synonyms: … coagulation factor II …
Matched Description: … These antibodies may subsequently cross-react with endogenous human factor V and lead to its deficiency ... Medical thrombin is a protein substance produced through a conversion reaction in which prothrombin of ... regulating hemostasis and maintaining blood coagulation. …
Matched Mixtures name: … TISSEEL FIBRIN SEALANT VH S/D (FROZEN) …
Matched Categories: … Increased Coagulation Factor Activity ... Protein Precursors ... Prothrombin, agonists ... Blood Coagulation Factors ... Enzymes and Coenzymes …
Protein C is an endogenously occurring plasma protein that plays a key role within the coagulation cascade. Protein C is a zymogen, or enzyme precursor, of a vitamin K-dependent anticoagulant glycoprotein (serine protease) that is synthesized in the liver. It is converted by the thrombin/thrombomodulin-complex on the endothelial cell surface...
Approved
Matched Synonyms: … blood coagulation factor XIV ... Protein C (coagulation inhibitor) ... Human protein C
Matched Name: … Protein C
Matched Description: … The Protein C pathway provides a natural mechanism for control of the coagulation system and prevention ... S. ... Protein C is an endogenously occurring plasma protein that plays a key role within the coagulation cascade …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … protein C ... Blood Coagulation Factor Inhibitors ... Decreased Coagulation Factor Activity ... Protein Precursors ... Enzymes and Coenzymes …
Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor VIII (FVIII) product that has recently been approved for the treatment of bleeding episodes in adults with acquired haemophilia A (AHA). AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the...
Approved
Investigational
Matched Synonyms: … CELLS: DES-(753-1418)-BLOOD-COAGULATION FACTOR VIII (PROCOAGULANT COMPONENT) SUS SCROFA, GLYCOSYLATED ... Antihemophilic factor (recombinant) porcine sequence ... ANTIHEMOPHILIC FACTOR (RECOMBINANT), PORCINE SEQUENCE …
Matched Description: … These autoantibodies neutralize circulating human factor VIII and create a functional deficiency of this ... procoagulant protein. ... Patients with AHA have normal Factor VIII genes for coagulation pathways but develop inhibitory autoantibodies …
Matched Categories: … Blood Coagulation Factors ... Blood and Blood Forming Organs …
Turoctocog alfa pegol is a pegylated version of turoctocog alfa. Novo Nordisk's brand name Esperoct (turoctocog alfa pegol, N8-GP) was approved by the US FDA on February 19, 2019. Fundamentally, the N8-GP moiety is identical to turoctocog alfa, a recombinant human clotting factor VIII (rFVIII) with a truncated B-domain made...
Approved
Matched Synonyms: … Antihemophilic factor (recombinant), glycopegylated-exei …
Matched Description: … Fundamentally, the N8-GP moiety is identical to [turoctocog alfa], a recombinant human clotting factor ... acid 720, and a monoclonal antibody binding C-terminal to this position is used in the purification ... VIII molecule for factor VIII replacement therapy in patients with factor VIII deficiency, or hemophilia …
Matched Categories: … Factor VIII ... Blood Coagulation Factors ... Amino Acids, Peptides, and Proteins …
Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H)...
Approved
Investigational
Matched Synonyms: … Recombinant human coagulation factor IX, FC Fusion protein ... Coagulation factor IX recombinant immunoglubulin g1 fusion protein
Matched Description: … It is an X-linked genetic disease caused by mutation of the gene for coagulation protein factor IX (FIX ... It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region ... ), leading to decreased levels of endogenous factor IX and increased susceptibility to recurrent bleeding …
Matched Categories: … Protein Precursors ... Blood Coagulation Factors ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Kappadione is a Vitamin K derivative (chemically, it is menadiol sodium diphosphate), previously approved by FDA prior to 1982 and marketed by Lilly Marketing for this drug has been discontinued and is not available in North America . It has been found to have carcinogenic potential in mammalian cells as...
Approved
Matched Description: … derivative (chemically, it is menadiol sodium diphosphate), previously approved by FDA prior to 1982 and ... marketed by Lilly Marketing for this drug has been discontinued and is not available in North America …
Edoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting, oral, selective factor Xa inhibitor. By inhibiting factor Xa, a key protein in the coagulation cascade, edoxaban prevents the stepwise amplification of protein factors needed to form blood clots. It is indicated...
Approved
Matched Iupac: … 5-chloropyridin-2-yl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-{5-methyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c] …
Matched Description: … By inhibiting factor Xa, a key protein in the coagulation cascade, edoxaban prevents the stepwise amplification ... , oral, selective factor Xa inhibitor. ... of protein factors needed to form blood clots. …
Matched Categories: … Blood and Blood Forming Organs ... Factor Xa Inhibitors ... Direct factor Xa inhibitors …
Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor. Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated risk for excessive bleeding caused by spontaneous or secondary events like trauma...
Approved
Experimental
Matched Description: … Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor ... Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional ... VIII, which is caused by defects in the F8C gene that encodes coagulation factor VIII. …
Matched Categories: … Factor VIII ... Protein Precursors ... Blood Coagulation Factors ... Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 1500IU Powder and Solvent for Solution for Injection ... ADYNOVATE 2000IU Powder and Solvent for Solution for Injection ... ADYNOVATE 1000IU Powder and Solvent for Solution for Injection …
Displaying all 15 drugs