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Produced in CHO cell cultures, trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein (HER2). It is used as a treatment of human epidermal...
Approved
Investigational
Matched Synonyms: … Trastuzumab ... trastuzumab-anns ... trastuzumab-dkst …
Matched Name: … Trastuzumab
Matched Description: … Produced in CHO cell cultures, trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody ... Trastuzumab binds to HER2 and suppresses cancer cell growth, proliferation, and survival directly and ... [L14015] It is used as a treatment of human epidermal growth factor receptor (HER)-2+ metastatic breast …
Matched Categories: … pertuzumab and trastuzumab ... trastuzumab ... HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … ZUHERA Trastuzumab for Injection (rDNA Origin) 150mg/vial ... ZUHERA Trastuzumab for Injection (rDNA Origin) 440 mg/vial ... Herzuma (trastuzumab) 150 mg Powder for Concentrate for Solution for Infusion …
Pertuzumab is a recombinant humanized monoclonal antibody that targets the extracellular dimerization domain (subdomain II) of the human epidermal growth factor receptor 2 protein (HER2). It consists of two heavy chains and two lights chains that have 448 and 214 residues respectively. It was first approved by the FDA in...
Approved
Matched Synonyms: … Pertuzumab
Matched Name: … Pertuzumab
Matched Description: … Pertuzumab is a recombinant humanized monoclonal antibody that targets the extracellular dimerization ... domain (subdomain II) of the human epidermal growth factor receptor 2 protein (HER2). ... antibody, [trastuzumab], in the treatment of metastatic HER2-positive breast cancer. …
Matched Categories: … pertuzumab and trastuzumab ... pertuzumab ... HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Displaying all 2 drugs