Advanced Filter

Filter by Group

Filter by Market Availability

Displaying drugs 1 - 25 of 77 in total
Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Synonyms: … Insulin, aspart, human ... Insulin, aspart protamine, human ... Aspart Insulin
Matched Name: … Insulin aspart …
Matched Description: … produced human insulin, a peptide hormone produced by beta cells of the pancreas that promotes glucose ... Compared to human insulin, it has a single amino acid substitution at position B28 where proline is replaced ... Use of basal and bolus insulin together is intended to mimic the pancreas' production of endogenous insulin
Matched Categories: … insulin degludec and insulin aspart ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Insulin ... Insulin Analog …
Matched Products: … .Insulin Aspart Protamine and Insulin Aspart ... Insulin Aspart Protamine and Insulin Aspart Mix 70/30 ... Insulin Aspart …
Insulin glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Synonyms: … Insulin glulisine ... Insulin glulisine recombinant ... Insulin Glulisine (recombinant DNA origin) …
Matched Name: … Insulin glulisine …
Matched Description: … and increase the rate of absorption and onset of action compared to human insulin. ... Insulin glulisine is a biosynthetic, rapid-acting human insulin analogue produced in a non-pathogenic ... produced human insulin, a peptide hormone produced by beta cells of the pancreas that promotes glucose …
Matched Categories: … Insulin ... Insulin Analog ... insulin glulisine ... Insulin, Short-Acting ... Alimentary Tract and Metabolism …
Human Insulin, also known as Regular Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin. Typically prescribed for the management of diabetes mellitus,...
Approved
Investigational
Matched Synonyms: … Human insulin ... Insulin human ... Insulin (human) …
Matched Name: … Insulin human
Matched Description: … Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin ... Human Insulin, also known as Regular Insulin, is a short-acting form of insulin used for the treatment ... Human insulin is also available in an inhalable form, intended to be used as a bolus meal-time insulin
Matched Mixtures name: … Humulin 30/70 (insulin Human Biosynth Inj) ... Humulin 30/70 (insulin Human Biosynth Inj) …
Matched Salts name: … Insulin human zinc suspension ... NPH insulin
Matched Categories: … insulin (human) ... insulin (human) ... insulin (human) ... insulin (human) ... insulin (human) …
Matched Products: … Insulin Human Winthrop Rapid ... Insulin Human Winthrop Basal ... Insulin Human Winthrop Comb 15 …
Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the pancreas...
Approved
Matched Synonyms: … Insulin,lispro,human/rDNA ... Insulin lispro ... insulin lispro-aabc …
Matched Name: … Insulin lispro …
Matched Description: … human insulin in that the amino acid proline at position B28 is replaced by lysine and the lysine in ... human insulin, a peptide hormone produced by beta cells of the pancreas that promotes glucose metabolism ... then to a monomer that is absorbed more rapidly after subcutaneous injection compared to endogenous human
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Insulin ... Insulins and Analogues for Injection, Fast-Acting ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25 KwikPen ... Insulin lispro ... Insulin Lispro …
Exenatide is a glucagon-like peptide-1 (GLP-1) analog . It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control . Exenatide was given FDA approval on April 28, 2005 . It is available as immediate- and extended-release formulations.[L42685,L42690] Bydureon, the brand...
Approved
Investigational
Matched Description: … It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows ... It is available as immediate- and extended-release formulations. …
Matched Categories: … Fluids and Secretions ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … BYDUREON 2 mg powder and solvent for prolonged-release suspension for injection ... BYDUREON POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLED PEN 2MG …
Approved
Experimental
Metreleptin, a recombinant analog of the human hormone leptin, is an orphan drug used to treat complications of leptin deficiency in people with lipodystrophy. Lipodystrophies include a range of disorders characterized by the reduction, absence, or altered distribution of adipose tissue. Complications of lipodystrophy include metabolic abnormalities such as hypertriglyceridemia,...
Approved
Matched Description: … Metreleptin is produced in _E. coli_ and differs from native human leptin by the addition of a methionine ... resistance, reduced HbA1c and fasting glucose, reduced triglycerides, and reductions in food intake. ... Metreleptin, a recombinant analog of the human hormone leptin, is an orphan drug used to treat complications …
Matched Categories: … Amino Acids and Derivatives ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Sotalol is a methanesulfonanilide developed in 1960. It was the first of the class III anti arrhythmic drugs. Sotalol was first approved as an oral tablet on 30 October 1992. A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous injection indicated for life threatening...
Approved
Matched Description: … injection indicated for life threatening ventricular arrhythmias and maintaining normal sinus rhythm ... [L6334] A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous …
Matched Categories: … sotalol and thiazides ... Beta Blocking Agents and Thiazides ... sotalol and acetylsalicylic acid ... Beta Blocking Agents, Non-Selective, and Thiazides …
Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes mellitus (T2DM). It is sold by Sanofi-Aventis under the brand name Adlyxin in the US and Lyxumia in the EU. Adlyxin recieved FDA approval July 28, 2016.
Approved
Matched Description: … It is sold by Sanofi-Aventis under the brand name Adlyxin in the US[L763] and Lyxumia in the EU. …
Matched Mixtures name: … LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) ... LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) …
Matched Categories: … insulin glargine and lixisenatide ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control. Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive...
Approved
Matched Description: … increasing the insulin-mediated peripheral glucose uptake. ... resistance in accordance with progressive β cell failure and long-term microvascular and macrovascular ... Sulfonylureas are one of the insulin secretagogues widely used for the management of type 2 diabetes …
Matched Mixtures name: … Pioglitazone and Glimepiride ... Pioglitazone and Glimepiride ... Pioglitazone hydrochloride and glimepiride …
Matched Categories: … Insulin Secretagogues ... Alimentary Tract and Metabolism ... glimepiride and pioglitazone ... glimepiride and rosiglitazone …
Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK) and epidermal growth factor receptor (EGFR). It presents selectivity against the mutant forms of EGFR compared to the wild-type. It also exhibits selectivity against 9 different Crizotinib-resistant mutants of the EML4-ALK fusion gene, which is a...
Approved
Investigational
Matched Description: … Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK) and ... Brigatinib was developed by Ariad Pharmaceuticals, a subsidiary of Takeda Pharmaceutical Company Limited, and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to...
Approved
Investigational
Matched Mixtures name: … Telmisartan and Amlodipine ... Telmisartan and Amlodipine ... Telmisartan and Amlodipine …
Matched Categories: … telmisartan and diuretics ... telmisartan and amlodipine ... telmisartan, amlodipine and hydrochlorothiazide ... Angiotensin II receptor blockers (ARBs) and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers …
Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive. As well, moxonidine has been shown...
Approved
Investigational
Matched Description: … As well, moxonidine has been shown to present blood pressure-independent beneficial effects on insulin ... suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and
Matched Categories: … moxonidine and diuretics …
Macimorelin, a novel and orally active ghrelin mimetic that stimulates GH secretion, is used in the diagnosis of adult GH deficiency (AGHD). More specifically, macimorelin is a peptidomimetic growth hormone secretagogue (GHS) that acts as an agonist of GH secretagogue receptor, or ghrelin receptor (GHS-R1a) to dose-dependently increase GH levels...
Approved
Investigational
Matched Description: … fat mass (particularly in the abdominal region), decreased lean body mass, osteopenia, dyslipidemia, insulin ... such as AIDS and cancer. ... resistance, and/or glucose intolerance overtime. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Description: … studies to significantly reduce the risk of development of CVD and all-cause mortality. ... belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and ... of metabolic reactions involved in the production of several compounds involved in lipid metabolism and
Matched Mixtures name: … Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe …
Matched Categories: … Alimentary Tract and Metabolism ... rosuvastatin and ramipril ... rosuvastatin and valsartan ... rosuvastatin and ezetimibe ... rosuvastatin and amlodipine …
Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Synonyms: … Insulin glargine ... insulin glargine-yfgn ... Insulin glargine recombinant …
Matched Name: … Insulin glargine …
Matched Description: … Insulin glargine differs from endogenous human insulin by the replacement of an asparagine residue at ... produced human insulin, a peptide hormone produced by beta cells of the pancreas that promotes glucose ... Basal insulin is often combined with short-acting "bolus insulin" such as [DB00046], [DB01309], and [ …
Matched Categories: … insulin glargine and lixisenatide ... Alimentary Tract and Metabolism ... Insulin ... Amino Acids, Peptides, and Proteins ... Insulin Analog …
Matched Products: … Insulin Glargine ... Insulin glargine U-300 ... Insulin Glargine Solostar …
Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A2358, A2359, A2360, A44] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta...
Approved
Matched Synonyms: … Insulin,detemir,human ... Insulin detemir ... Insulin detemir recombinant …
Matched Name: … Insulin detemir …
Matched Description: … mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells ... [DB00046], [DB01309], and [DB01306] to provide higher doses of insulin required following meals. ... [A2358, A2359, A2360, A44] Use of basal and bolus insulin together is intended to mimic the pancreas' …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Insulin ... Insulin Analog ... insulin detemir …
Insulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A18561,A18562,A18563,A18564,A174934] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Synonyms: … Insulin degludec …
Matched Name: … Insulin degludec …
Matched Description: … mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by ... Use of basal and bolus insulin together is intended to mimic the pancreas' production of endogenous insulin ... and skeletal muscle. …
Matched Categories: … insulin degludec and insulin aspart ... insulin degludec and liraglutide ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Insulin
Matched Products: … Insulin Degludec …
Mecasermin rinfabate is approved for severe primary insulin-like growth factor (IGF) deficiency or in patients with GH gene deletion who have developed antibodies to growth hormone (GH) . Mecasermin rinfabate is similar to DB01277 in that both drugs contain recombinant DNA origin insulin-like growth factor 1 (IGF-1). Mecasermin rinfabate however,...
Approved
Matched Synonyms: … Recombinant human insulin-like growth factor-I/insulin-like growth factor binding protein-3 …
Matched Description: … The binding of IGF-1 to IGFBP-3 is said to extend the half life and reduce the clearance of IGF-1 in ... patients with growth hormone resistant syndromes and low levels of IGFBP-3 though this may represent ... Mecasermin rinfabate is approved for severe primary insulin-like growth factor (IGF) deficiency or in …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Somatropin and Somatropin Agonists ... Anterior Pituitary Lobe Hormones and Analogues …
Teprotumumab is a fully human IgG1 monoclonal antibody directed against the human insulin-like growth factor-1 receptor. Following a clinical trial in which its efficacy in the treatment of thyroid eye disease (TED) was assessed, it received "breakthrough therapy" designation from the FDA in 2016 and was approved by the FDA...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human insulin-like growth factor I receptor) (human monoclonal heavy chain), ... disulfide with human monoclonal light chain, dimer …
Matched Description: … Teprotumumab is a fully human IgG1 monoclonal antibody directed against the human insulin-like growth ... tissue remodeling behind the eye, and previous treatment options typically involved multiple invasive ... disease (TED) was assessed, it received "breakthrough therapy" designation from the FDA in 2016[A190129] and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Insulin-like Growth Factor-1 Receptor Inhibitor ... Insulin-like Growth Factor-1 Receptor Inhibitors …
Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label]. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons. The amino acid sequence of the product is identical to that of endogenous human IGF-1. The rhIGF-1 protein is...
Approved
Investigational
Matched Synonyms: … INSULIN-LIKE GROWTH FACTOR I (HUMAN) ... RECOMBINANT HUMAN INSULIN-LIKE GROWTH FACTOR-I ... Human somatomedin C …
Matched Description: … Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label ... IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a ... The amino acid sequence of the product is identical to that of endogenous human IGF-1. …
Matched Categories: … Human Insulin-like Growth Factor Analogs ... Recombinant Human Insulin-like Growth Factor-1 ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins …
Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood...
Approved
Investigational
Matched Synonyms: … Human growth hormone ... Somatotropin human ... Growth hormone (human) …
Matched Description: … Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and ... It has an identical primary protein structure to endogenous human growth hormone. ... fat mass regulation, blood glucose level regulation, and lipid regulation in both children and adults …
Matched Categories: … Recombinant Human Growth Hormone ... Human Growth Hormone, antagonists & inhibitors ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins …
Matched Products: … ZOMACTON Powder and Solvent for Solution for Injection 10mg ... ZOMACTON Powder and Solvent for Solution for Injection 4 mg ... GENOTROPIN® 12MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Somatrogon is a long-acting recombinant human growth hormone. Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood. Recombinant growth hormone therapy for growth hormone deficiency and other conditions has...
Approved
Matched Synonyms: … .)-(118-145)-PEPTIDE (1-28) WITH HUMAN SOMATOTROPIN (GROWTH HORMONE, GH) (29-219) AND TWO TANDEM COPIES ... (HUMAN .BETA. ... 118-145-GONADOTROPIN, CHORIONIC (HUMAN .BETA. …
Matched Description: … chorionic gonadotropin (hCG) to the N-terminus and C-terminus of human growth hormone. ... Somatrogon is a long-acting recombinant human growth hormone. ... three copies of the C-terminal peptide (CTP), or 28 carboxy-terminal residues, from the beta chain of human
Matched Categories: … Recombinant Human Growth Hormone ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Somatropin and Somatropin Agonists …
Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Synonyms: … Teriparatide recombinant human
Matched Description: … [A251395] It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. ... Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. ... [A251395] Teriparatide is used in the treatment of osteoporosis in men and women.[L42590, L42595] …
Matched Categories: … Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Parathyroid Hormones and Analogues ... Calcium-Regulating Hormones and Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Pramlintide is a relatively new adjunct treatment for diabetes (both type 1 and 2), developed by Amylin Pharmaceuticals. It is derived from amylin, a hormone that is released into the bloodstream, in a similar pattern as insulin, after a meal. Like insulin, amylin is deficient in individuals with diabetes.
Approved
Investigational
Matched Description: … Pramlintide is a relatively new adjunct treatment for diabetes (both type 1 and 2), developed by Amylin ... Like insulin, amylin is deficient in individuals with diabetes. ... It is derived from amylin, a hormone that is released into the bloodstream, in a similar pattern as insulin
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Displaying drugs 1 - 25 of 77 in total