Identification
- Generic Name
- Pork collagen
- DrugBank Accession Number
- DB14100
- Background
Pork Collagen is used within MACI® (autologous cultured chondrocytes on porcine collagen membrane) as an autologous cellularized scaffold product indicated for the repair of single or multiple symptomatic, full-thickness cartilage defects of the knee with or without bone involvement in adults. It serves as an alternative repair treatment for patients with inadequate response to pre-existing surgical methods. The surgical implantation shows a tolerable safety profile and efficacy up to 4 years, but it is not indicated for patients with osteoarthritis. It has been used since 1995 as Carticel and gained biologic license in 1997. The surgical implantation was first performed in Sweden.
- Type
- Biotech
- Groups
- Approved, Investigational
- Synonyms
- Collagen Porcine
- Collagen, Porcine
Pharmacology
- Indication
indicated for the repair of single or multiple symptomatic, full-thickness cartilage defects of the knee with or without bone involvement in adults.
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Treatment of Cartilage damage •••••••••••• ••••• •••••• •• •••••••• ••••••••••• •••••••••••••• ••••••••• ••••••• •••• •• ••••••• •••• ••••••••••• - Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- No interactions found.
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Gynecological Gel Pork collagen (6.25 g/25mL) + Propolis wax (5 g/25mL) + Safflower (3.75 g/25mL) + Sophora flavescens root (2.5 g/25mL) Gel Cutaneous Shantou Youjia E-Commerce Co., Ltd. 2024-02-01 2024-12-31 US 
Le-Blen Nano Collagen Peptide Serum Pork collagen (0.54 g/56.7g) + Glycerin (14.18 g/56.7g) + Sodium hyaluronate (0.54 g/56.7g) Lotion Topical LeBlen Beauty Inc 2018-04-24 Not applicable US Maci Pork collagen (15 cm2/1) + Autologous cultured chondrocytes (15000000 1/1) Implant Intra-articular Vericel Corporation 2017-06-09 Not applicable US P3 Rg Pork collagen (0.19 g/100g) + Glycerin (10 g/100g) Gel Topical CONTRAD SWISS 2019-03-31 Not applicable US P3 Rg Pork collagen (0.19 g/100g) + Glycerin (10 g/100g) Gel Topical SIPRES SRL 2021-11-08 Not applicable US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Le-Blen Nano Collagen Peptide Serum Pork collagen (0.54 g/56.7g) + Glycerin (14.18 g/56.7g) + Sodium hyaluronate (0.54 g/56.7g) Lotion Topical LeBlen Beauty Inc 2018-04-24 Not applicable US
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- I8442U2G7J
- CAS number
- Not Available
References
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Gel Cutaneous Lotion Topical Implant Intra-articular Gel Topical - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Solid
- Experimental Properties
- Not Available
Drug created at June 19, 2018 17:16 / Updated at September 28, 2021 21:54