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Displaying drugs 1 - 25 of 58 in total

Benzoyl peroxide

Benzoyl peroxide is a commonly used drug in topical treatments for acne.[L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically interact with proteins.[A18903,A233859] This treatment decreases keratin and...
Approved
Matched Synonyms: … Benzoyl peroxide ... Benzoyl benzenecarboperoxoate …
Matched Name: … Benzoyl peroxide …
Matched Iupac: … benzoyl benzenecarboperoxoate …
Matched Description: … Benzoyl peroxide is a commonly used drug in topical treatments for acne. ... [A234059,A234064,A234069] Benzoyl peroxide, in combination with erythromycin, was granted FDA approval ... [A18903,A233859] This treatment decreases keratin and sebum around follicles, as well as increasing turnover …
Matched Mixtures name: … Acne Vanishing Gel- 10% with Sulfur ... Adapalene and Benzoyl Peroxide ... ADAPALENE and BENZOYL PEROXIDE …
Matched Categories: … benzoyl peroxide ... benzoyl peroxide, combinations …
Matched Products: … Benzoyl Peroxide ... Benzoyl Peroxide Wash ... Benzoyl Peroxide 4 …

Benfotiamine

Benfotiamine has been investigated for the treatment and prevention of Diabetic Nephropathy and Diabetes Mellitus, Type 2.
Approved
Experimental
Matched Description: … Benfotiamine has been investigated for the treatment and prevention of Diabetic Nephropathy and Diabetes …
Matched Categories: … Sulfur Compounds ... Alimentary Tract and Metabolism …

Bismuth subgallate

Bismuth subgallate is a yellow colored substance that presents as an odorless powder that undergoes discoloration when exposed to sunlight. It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet...
Approved
Matched Description: … It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. ... Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet elucidated ... antimicrobial and hemostatic actions, bismuth subgallate is most commonly available as an over-the-counter …
Matched Categories: … Antacids and Adsorbents …

Fezolinetant

Vasomotor symptoms (VMS), more colloquially known as hot flashes or night sweats, are some of the most common symptoms in menopause. With a median duration of 7.4 years, vasomotor symptoms are also the most common reasons why women seek treatments for menopausal issues.[A259591,A259596] Although mostly considered a nuisance, vasomotor symptoms...
Approved
Investigational
Matched Description: … severe VMS daily have reported a decline in sleep quality, concentration, sexual activity, energy, and ... [A259606] Estrogen is a potent neuromodulator, particularly in the hypothalamus, and has been shown to ... increase neurokinin B signalling, increasing the activity of KNDy neurons and therefore the activity …
Matched Categories: … Sulfur Compounds ... Genito Urinary System and Sex Hormones …

Phthalylsulfathiazole

Phthalylsulfathiazole is a broad spectrum antibiotic which is part of the drug class, sulfonamides. It was used as an antibiotic for bowel surgery, and for infections of the colon .
Approved
Matched Description: … It was used as an antibiotic for bowel surgery, and for infections of the colon [A175006]. …
Matched Categories: … Sulfur Compounds ... Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Acetohexamide

A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. Acetohexamide has been discontinued in the US market.
Approved
Investigational
Withdrawn
Matched Categories: … Sulfur Compounds ... Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Meticillin

One of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.
Approved
Investigational
Matched Categories: … Sulfur Compounds …

Eprosartan

Eprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. By inhibiting norepinephrine production, blood pressure is further reduced.
Approved
Matched Description: … By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs …
Matched Categories: … Sulfur Compounds ... eprosartan and diuretics ... Angiotensin II receptor blockers (ARBs) and diuretics …

Ertapenem

Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Description: … [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic ... [L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. …
Matched Categories: … Sulfur Compounds …

Sulfasalazine

Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal anti-inflammatory drugs. It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA).[L39065, A255582] Metabolized by intestinal bacteria, sulfasalazine is broken down into mesalazine and sulfapyridine, 2 compounds that carry out the main pharmacological...
Approved
Matched Description: … Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal ... It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis ... L39065, A255582] Metabolized by intestinal bacteria, sulfasalazine is broken down into [mesalazine] and …
Matched Categories: … Sulfur Compounds ... Alimentary Tract and Metabolism …

Vemurafenib

Vemurafenib is a competitive kinase inhibitor with activity against BRAF kinase with mutations like V600E. It exerts its function by binding to the ATP-binding domain of the mutant BRAF. Vemurafenib was co-developed by Roche and Plexxikon and it obtained its FDA approval on August 17, 2011, under the company Hoffmann...
Approved
Matched Description: … [A31270] Vemurafenib was co-developed by Roche and Plexxikon and it obtained its FDA approval on August …
Matched Categories: … Sulfur Compounds ... Antineoplastic and Immunomodulating Agents ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Zafirlukast

Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once...
Approved
Investigational
Matched Description: … It is available as a tablet and is usually dosed twice daily. ... on the CysLT1 receptors, thus reducing constriction of the airways, build-up of mucus in the lungs and ... antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and …
Matched Categories: … Sulfur Compounds ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Spironolactone

Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered.[A11837, A178246] It is indicated to treat several conditions, including...
Approved
Matched Description: … [A178192] It promotes sodium and water excretion and potassium retention. ... It binds to mineralocorticoid receptors and functions as aldosterone antagonists. ... [L44602] Off-label uses of spironolactone include hirsutism, female pattern hair loss, and adult acne …
Matched Mixtures name: … Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2% ... Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2% / Tretinoin 0.05% ... Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2% / Tretinoin 0.025% …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Salicylic acid

A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Approved
Investigational
Vet approved
Matched Description: … A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically ... It has bacteriostatic, fungicidal, and keratolytic actions. …
Matched Mixtures name: … Dermaharmony Sulfur and Salicylic Acid ... Dermaharmony Sulfur and Salicylic Acid ... Sulfur …
Matched Categories: … Salicylic Acid and Derivatives …
Matched Products: … Sulfur 8 Loc Twist and Braid Scalp ... Sulfur 8 Fresh Anti-Dandruff Hair and Scalp Conditioner ... Sulfur 8 Anti-Dandruff Braid …

Meradimate

Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter. It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved by the FDA and Health Canada to be used as an...
Approved
Matched Description: … Meradimate is approved by the FDA and Health Canada to be used as an ingredient in sunblocking products …
Matched Mixtures name: … Sodium Sulfacetamide Sulfur ... Principal Secret Reclaim Sunscreen For Face and Body SPF 30 …

Bumetanide

Bumetanide is a sulfamyl diuretic.
Approved
Matched Categories: … Sulfur Compounds ... bumetanide and potassium ... Genito Urinary System and Sex Hormones ... bumetanide and potassium-sparing agents ... Gynecological Antiinfectives and Antiseptics …

Venetoclax

Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label]. Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed cell death) process , . Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types...
Approved
Investigational
Matched Description: … Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types of small lymphocytic …
Matched Categories: … Sulfur Compounds ... Antineoplastic and Immunomodulating Agents …

Nicotinamide

An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Approved
Investigational
Matched Description: … Its primary significance is in the prevention and/or cure of blacktongue and pellagra. ... Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and …
Matched Mixtures name: … Benzoyl Peroxide 8% / Niacinamide 4% ... Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 4% ... Benzoyl Peroxide 2.5% / Clindamycin 1% / Niacinamide 4% …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Dr.g Lock and More A-clear Mask ... P8 Tone - Up and Brightening CreamEX ... HANSKIN BiO FILL PEP MASK Firming and Moisture …

Sulfabenzamide

Sulfabenzamide is an antimicrobial agent often used in conjunction with sulfathiazole and sulfacetamide as a topical intravaginal antibacterial preparation.
Approved
Matched Description: … Sulfabenzamide is an antimicrobial agent often used in conjunction with sulfathiazole and sulfacetamide …
Matched Categories: … Sulfur Compounds …

Nitazoxanide

Nitazoxanide belongs to the class of drugs known as thiazolides. Nitazoxanide (NTZ) is a broad-spectrum anti-infective drug that markedly modulates the survival, growth, and proliferation of a range of extracellular and intracellular protozoa, helminths, anaerobic and microaerophilic bacteria, in addition to viruses. This drug is effective in the treatment of...
Approved
Investigational
Vet approved
Matched Description: … proliferation of a range of extracellular and intracellular protozoa, helminths, anaerobic and microaerophilic ... Nitazoxanide (NTZ) is a broad-spectrum anti-infective drug that markedly modulates the survival, growth, and ... children and may also be considered in the treatment of illnesses caused by other protozoa or helminths …
Matched Categories: … Sulfur Compounds ... Antiparasitic Products, Insecticides and Repellents …

Lusutrombopag

Lusutrombopag is an orally bioavailable thrombopoietin receptor (TPOR) agonist developed by Shionogi & Company (Osaka, Japan). TPOR is a regulatory target site for endogenous thrombopoietin, which acts as a primary cytokine to promote megakaryocyte proliferation and differentiation, and affect other hematopoietic lineages as well, including erythroid, granulocytic and lymphoid lineages...
Approved
Investigational
Matched Description: … and lymphoid lineages [A36736]. ... endogenous thrombopoietin, which acts as a primary cytokine to promote megakaryocyte proliferation and ... differentiation, and affect other hematopoietic lineages as well, including erythroid, granulocytic …
Matched Categories: … Sulfur Compounds ... Blood and Blood Forming Organs …

Piretanide

Piretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine residues in an aromatic nucleus in the presence of other aromatically bonded functional groups.
Approved
Matched Categories: … Sulfur Compounds ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Probenecid

The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
Approved
Investigational
Matched Description: … It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. ... Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal …
Matched Mixtures name: … Probenecid and Colchicine ... Probenecid and Colchicine ... Probenecid and Colchicine …
Matched Categories: … Sulfur Compounds ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Indapamide

The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor to all-cause mortality is hypertension. Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. Treatment for hypertension should include a number of lifestyle changes (ie. reduced...
Approved
Matched Description: … The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor ... [A204155] Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts ... Thiazide-like diuretics such as indapamide are a valuable tool for the treatment of hypertension and …
Matched Categories: … Sulfur Compounds ... Genito Urinary System and Sex Hormones ... perindopril, amlodipine and indapamide ... rosuvastatin, perindopril and indapamide …

Furosemide

Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It...
Approved
Vet approved
Matched Description: … Furosemide has a fast onset and short duration of action and has been used safely and effectively in ... both pediatric and adult patients. ... In addition to oral formulations, the solution for intravenous and intramuscular administration is also …
Matched Categories: … Sulfur Compounds ... furosemide and potassium ... furosemide and potassium-sparing agents ... High-Ceiling Diuretics and Potassium-Sparing Agents …
Displaying drugs 1 - 25 of 58 in total