IdentifierDBSNPE005870
DrugDB00675 (Tamoxifen)
Interacting Gene/EnzymeCytochrome P450 2D6
Gene NameCYP2D6
UniProt IDP10635
Defining Change(s)
Allele NameCYP2D6*19
Genotype(s)Not Available
Type(s)Effect Inferred
GroupsNon-functional CYP2D6
DescriptionPoor response to drug treatment, shorter time to relapse
References
  1. Marez D, Legrand M, Sabbagh N, Lo Guidice JM, Spire C, Lafitte JJ, Meyer UA, Broly F: Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: characterization of 48 mutations and 53 alleles, their frequencies and evolution. Pharmacogenetics. 1997 Jun;7(3):193-202. [PubMed:9241659 ]
  2. The Human Cytochrome P450 (CYP) Allele Nomenclature Database [Link]