IdentifierDBSNPE005878
DrugDB00675 (Tamoxifen)
Interacting Gene/EnzymeCytochrome P450 2D6
Gene NameCYP2D6
UniProt IDP10635
Defining Change(s)
2950G>CNot Available
Allele NameCYP2D6*44
Genotype(s)Not Available
Type(s)Effect Inferred
GroupsNon-functional CYP2D6
DescriptionPoor response to drug treatment, shorter time to relapse
References
  1. Yamazaki H, Kiyotani K, Tsubuko S, Matsunaga M, Fujieda M, Saito T, Miura J, Kobayashi S, Kamataki T: Two novel haplotypes of CYP2D6 gene in a Japanese population. Drug Metab Pharmacokinet. 2003;18(4):269-71. [PubMed:15618746 ]
  2. The Human Cytochrome P450 (CYP) Allele Nomenclature Database [Link]